Jose Guevara-Patino, MD, PhD

Associate Professor
Surgical Research

Education

ADVANCED DEGREES
National Institute for Medical Research, London, FR, United Kingdom
MEDICAL SCHOOL
Universidad Central de Venezuela

Mutant HSP70 reverses autoimmune depigmentation in vitiligo Mosenson, J. A.; Zloza, A.; Nieland, J. D.; Garrett-Mayer, E.; Eby, J. M.; Huelsmann, E. J.; Kumar, P.; Denman, C. J.; Lacek, A. T.; Kohlhapp, F. J.; Alamiri, A.; Hughes, T.; Bines, S. D.; Kaufman, H. L.; Overbeck, A.; Mehrotra, S.; Hernandez, C.; Nishimura, M. I.; Guevara-Patino, J. A.; Le Poole, I. C., Science translational medicine

CD8(+) T cells sabotage their own memory potential through IFN-gamma-dependent modification of the IL-12/IL-15 receptor alpha axis on dendritic cells Kohlhapp, F. J.; Zloza, A.; O'Sullivan, J. A.; Moore, T. V.; Lacek, A. T.; Jagoda, M. C.; McCracken, J.; Cole, D. J.; Guevara-Patino, J. A., Journal of immunology (Baltimore, Md.: 1950)

HSP70i is a critical component of the immune response leading to vitiligo. Mosenson, J. A.; Zloza, A.; Klarquist, J.; Barfuss, A. J.; Guevara-Patino, J. A.; Poole, I. C., Pigment Cell & Melanoma Research

NKG2D signaling on CD8(+) T cells represses T-bet and rescues CD4-unhelped CD8(+) T cell memory recall but not effector responses Zloza, A.; Kohlhapp, F. J.; Lyons, G. E.; Schenkel, J. M.; Moore, T. V.; Lacek, A. T.; O'Sullivan, J. A.; Varanasi, V.; Williams, J. W.; Jagoda, M. C.; Bellavance, E. C.; Marzo, A. L.; Thomas, P. G.; Zafirova, B.; Polic, B.; Al-Harthi, L.; Sperling, A. I.; Guevara-Patino, J. A., Nature medicine

CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-beta (TGF-beta)-mediated suppression Zloza, A.; Jagoda, M. C.; Lyons, G. E.; Graves, M. C.; Kohlhapp, F. J.; O'Sullivan, J. A.; Lacek, A. T.; Nishimura, M. I.; Guevara-Patino, J. A., Cancer immunology, immunotherapy : CII

Combination of epitope-optimized DNA vaccination and passive infusion of monoclonal antibody against HER2/neu leads to breast tumor regression in miceOrlandi, F.; Guevara-Patino, J. A.; Merghoub, T.; Wolchok, J. D.; Houghton, A. N.; Gregor, P. D., Vaccine

Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-beta blockade during the perioperative period of tumor resection Bellavance, E. C.; Kohlhapp, F. J.; Zloza, A.; O'Sullivan, J. A.; McCracken, J.; Jagoda, M. C.; Lacek, A. T.; Posner, M. C.; Guevara-Patino, J. A., Journal of immunology (Baltimore, Md.: 1950)

Engagement of NK receptor NKG2D but not 2B4, results in self-reactive CD8+ T cells and autoimmune vitiligo, Zloza, A.; Lyons, G. E.; Chlewicki, L. K.; Kohlhapp, F. J.; O'Sullivan, J. A.; Lacek, A. T.; Moore, T. V.; Jagoda, M. C.; Kumar, V.; Guevara-Patino, J. A., Autoimmunity

Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)beta-mediated suppression O'Sullivan, J. A.; Zloza, A.; Kohlhapp, F. J.; Moore, T. V.; Lacek, A. T.; Dulin, N. O.; Guevara-Patino, J. A., Cancer immunology, immunotherapy : CII

Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens Cote, A. L.; Zhang, P.; O'Sullivan, J. A.; Jacobs, V. L.; Clemis, C. R.; Sakaguchi, S.; Guevara-Patino, J. A.; Turk, M. J., Journal of immunology (Baltimore, Md.: 1950)

Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodiesLazarou, M.; Guevara-Patino, J. A.; Jennings, R. M.; McIntosh, R. S.; Shi, J.; Howell, S.; Cullen, E.; Jones, T.; Adame-Gallegos, J. R.; Chappel, J. A.; McBride, J. S.; Blackman, M. J.; Holder, A. A.; Pleass, R. J.,