Cancer & Signal Transduction

Maurizio Bocchetta, Ph.D. - Our research is focused on studying and fighting hypoxic tumor microenvironment

Eun-Kyoung Breuer, Ph.D. – The DNA damage response and cellular surveillance of genomic integrity

Kenneth L. Byron, Ph.D. - Signal transduction and ion channel regulation in vascular smooth muscle

Neil Clipstone, Ph.D. - The role of the calcineurin/NFAT-signaling pathway in cell growth and differentiation

Michael Collins, Ph.D. - Mediators/mechanisms of neurodegeneration and neuroprotection

Bruce Cuevas, Ph.D. - Signaling processes required for tumor progression and potential targets for therapeutic intervention in tumor metastasis

Mitchell Denning, Ph.D. - Role of protein kinase C isoforms in normal skin biology, the response of skin to ultraviolet radiation, and skin carcinogenesis

Saverio Gentile, Ph.D. - Modulation of ion channel activity in physiological and pathological conditions

Earle W. Holmes, Ph.D. – The biologic activities of melanin

Matthias Majetschak, M.D., Ph.D. - Intra- and extracellular functions of the ubiquitin proteasome system after injury and inflammation

Takeshi Shimamura, Ph.D. - Preclinical studies of signaling pathways in lung cancer using integrative genomics and proteomics

William Simmons, Ph.D. - Mechanism of inactivation of bradykinin, an important hormone in the cardiovascular system