Name
Gregory Mignery
Degree
Ph.D.
Rank
Professor
Primary Department
Cell and Molecular Physiology
Education
Advanced Degrees
Texas A&M University, College Station , College Station , TX , United States
Fellowships
University of Texas Southwestern Medical Center, Research
Hobbies
Astronomy
Camping
Paleontology
Keywords
Excitation-Contraction coupling
Gene Cloning
Gene Regulation
Biotechnology
Brain
Calcium Channel
Cardiovascular System
Channelopathies
Electrophysiology
Apoptosis
Arrhythmias
Publications
Pabbidi,M. R.; Ji,X.; Maxwell,J. T.; Mignery,G. A.; Samarel,A. M.; Lipsius,S. L.Inhibition of cAMP-Dependent PKA Activates beta2-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A2 via Raf-1/MEK/ERK and IP3-Dependent Ca2+ Signaling in Atrial Myocytes PLoS ONE 2016 ;11(12):e0168505
Sankar,N.; deTombe,P. P.; Mignery,G. A.Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling The Journal of biological chemistry 2014 ;289(9):6188-6198
Kapoor,N.; Maxwell,J. T.; Mignery,G. A.; Will,D.; Blatter,L. A.; Banach,K.Spatially Defined InsP3-Mediated Signaling in Embryonic Stem Cell-Derived Cardiomyocytes PLoS ONE 2014 ;9(1):e83715
Xu,L.; Pallikkuth,S.; Hou,Z.; Mignery,G. A.; Robia,S. L.; Han,R.Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells PLoS ONE 2011 ;6(11):e27884
Domeier,T. L.; Zima,A. V.; Maxwell,J. T.; Huke,S.; Mignery,G. A.; Blatter,L. A.IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in rabbit ventricular myocytes American Journal of Physiology - Heart & Circulatory Physiology 2008 ;294(2):H596-604
Zima,A. V.; Bare,D. J.; Mignery,G. A.; Blatter,L. A.IP3-dependent nuclear Ca2+ signalling in the mammalian heart. Journal of Physiology 2007 ;584(Pt 2):601-611
Kapur,N.; Mignery,G. A.; Banach,K.Cell cycle-dependent calcium oscillations in mouse embryonic stem cells. American Journal of Physiology - Cell Physiology 2007 ;292(4):1510-1518
Remus,T. P.; Zima,A. V.; Bossuyt,J.; Bare,D. J.; Martin,J. L.; Blatter,L. A.; Bers,D. M.; Mignery,G. A.Biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution. Journal of Biological Chemistry 2006 ;281(1):608-616
Bare,D. J.; Kettlun,C. S.; Liang,M.; Bers,D. M.; Mignery,G. A.Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. Journal of Biological Chemistry 2005 ;280(16):15912-15920
Guillemette,J.; Caron,A. Z.; Regimbald-Dumas,Y.; Arguin,G.; Mignery,G. A.; Boulay,G.; Guillemette,G.Expression of a truncated form of inositol 1,4,5-trisphosphate receptor type III in the cytosol of DT40 triple inositol 1,4,5-trisphosphate receptor-knockout cells. Cell calcium 2005 ;37(2):97-104
Chen,R.; Valencia,I.; Zhong,F.; McColl,K. S.; Roderick,H. L.; Bootman,M. D.; Berridge,M. J.; Conway,S. J.; Holmes,A. B.; Mignery,G. A.; Velez,P.; Distelhorst,C. W.Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. Journal of Cell Biology 2004 ;166(2):193-203
Tong,Q.; Chu,X.; Cheung,J. Y.; Conrad,K.; Stahl,R.; Barber,D. L.; Mignery,G.; Miller,B. A.Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R. American Journal of Physiology - Cell Physiology 2004 ;287(6):1667-1678
Ramos,J.; Jung,W.; Ramos-Franco,J.; Mignery,G. A.; Fill,M.Single channel function of inositol 1,4,5-trisphosphate receptor type-1 and -2 isoform domain-swap chimeras. Journal of General Physiology 2003 ;121(5):399-411
Serysheva,I. I.; Bare,D. J.; Ludtke,S. J.; Kettlun,C. S.; Chiu,W.; Mignery,G. A.Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy. Journal of Biological Chemistry 2003 ;278(24):21319-21322
Holtzclaw,L. A.; Pandhit,S.; Bare,D. J.; Mignery,G. A.; Russell,J. T.Astrocytes in adult rat brain express type 2 inositol 1,4,5-trisphosphate receptors. Glia 2002 ;39(1):69-84
Li,Y.; Kranias,E. G.; Mignery,G. A.; Bers,D. M.Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circulation research 2002 ;90(3):309-316
Galvan,D. L.; Mignery,G. A.Carboxyl-terminal sequences critical for inositol 1,4,5-trisphosphate receptor subunit assembly. Journal of Biological Chemistry 2002 ;277(50):48248-48260
Estrada,M.; Cardenas,C.; Liberona,J. L.; Carrasco,M. A.; Mignery,G. A.; Allen,P. D.; Jaimovich,E.Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors. Journal of Biological Chemistry 2001 ;276(25):22868-22874
Kockskamper,J.; Sheehan,K. A.; Bare,D. J.; Lipsius,S. L.; Mignery,G. A.; Blatter,L. A.Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes. Biophysical journal 2001 ;81(5):2590-2605
Ramos-Franco,J.; Bare,D.; Caenepeel,S.; Nani,A.; Fill,M.; Mignery,G.Single-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor. Biophysical journal 2000 ;79(3):1388-1399