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Seth Robia
Primary Department
Cell and Molecular Physiology
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Advanced Degrees
University of Wisconsin, Madison , Madison , WI , United States
Calcium Signaling
Lamichhane,R.; Mukherjee,S.; Smolin,N.; Pauszek,R. F.,3rd; Bradley,M.; Sastri,J.; Robia,S. L.; Millar,D.; Campbell,E. M.Dynamic conformational changes in the rhesus TRIM5alpha dimer dictate the potency of HIV-1 restriction Virology 2017 ;500:161-168
Dvornikov,A. V.; Smolin,N.; Zhang,M.; Martin,J. L.; Robia,S. L.; de Tombe,P. P.Restrictive cardiomyopathy Troponin-I R145W mutation does not perturb myofilament length dependent activation in human cardiac sarcomeres The Journal of biological chemistry 2016 ; :
Blackwell,D. J.; Zak,T. J.; Robia,S. L.Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer Biophysical journal 2016 ;111(6):1192-1202
Soller,K. J.; Verardi,R.; Jing,M.; Abrol,N.; Yang,J.; Walsh,N.; Vostrikov,V. V.; Robia,S. L.; Bowser,M. T.; Veglia,G.Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides Scientific reports 2015 ;5:13000
Abrol,N.; de Tombe,P. P.; Robia,S. L.Acute Inotropic and Lusitropic Effects of Cardiomyopathic R9C Mutation of Phospholamban The Journal of biological chemistry 2015 ;290(11):7130
Smolin,N.; Robia,S. L.A Structural Mechanism for Calcium Transporter Headpiece Closure The journal of physical chemistry.B 2015 ;119(4):1407-1415
Iram,S. H.; Gruber,S. J.; Raguimova,O. N.; Thomas,D. D.; Robia,S. L.ABC Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-throughput Screening Molecular pharmacology 2015 ;88(1):84-94
Iram,S. H.; Gruber,S. J.; Raguimova,O. N.; Thomas,D. D.; Robia,S. L.ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening Molecular pharmacology 2015 ;88(1):84-94
Abrol,N.; Smolin,N.; Armanious,G.; Ceholski,D. K.; Trieber,C. A.; Young,H. S.; Robia,S. L.Phospholamban C-terminal residues are critical determinants of the structure and function of the calcium ATPase regulatory complex The Journal of biological chemistry 2014 ;289(37):25855-25866
Sastri,J.; Johnsen,L.; Smolin,N.; Imam,S.; Mukherjee,S.; Lukic,Z.; Brandariz-Nunez,A.; Robia,S. L.; Diaz-Griffero,F.; Wiethoff,C.; Campbell,E. M.Restriction of HIV-1 by rhesus TRIM5alpha is governed by alpha helices in the Linker2 region Journal of virology 2014 ;88(16):8911-8923
Pallikkuth,S.; Blackwell,D. J.; Hu,Z.; Hou,Z.; Zieman,D. T.; Svensson,B.; Thomas,D. D.; Robia,S. L.Phosphorylated Phospholamban Stabilizes a Compact Conformation of the Cardiac Calcium-ATPase Biophysical journal 2013 ;105(8):1812-1821
Bidwell,P.; Blackwell,D. J.; Hou,Z.; Zima,A. V.; Robia,S. L.Phospholamban binds with differential affinity to calcium pump conformers. Journal of Biological Chemistry 2011 ;286(40):35044-35050
Koshman,Y. E.; Chu,M.; Engman,S. J.; Kim,T.; Iyengar,R.; Robia,S. L.; Samarel,A. M.Focal adhesion kinase-related nonkinase inhibits vascular smooth muscle cell invasion by focal adhesion targeting, tyrosine 168 phosphorylation, and competition for p130(Cas) binding. Arteriosclerosis, Thrombosis & Vascular Biology 2011 ;31(11):2432-2440
Lukic,Z.; Hausmann,S.; Sebastian,S.; Rucci,J.; Sastri,J.; Robia,S. L.; Luban,J.; Campbell,E. M.TRIM5alpha associates with proteasomal subunits in cells while in complex with HIV-1 virions Retrovirology 2011 ;8:93-4690-8-93
Song,Q.; Pallikkuth,S.; Bossuyt,J.; Bers,D. M.; Robia,S. L.Phosphomimetic mutations enhance oligomerization of phospholemman and modulate its interaction with the Na/K-ATPase. Journal of Biological Chemistry 2011 ;286(11):9120-9126
Xu,L.; Pallikkuth,S.; Hou,Z.; Mignery,G. A.; Robia,S. L.; Han,R.Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells PLoS ONE 2011 ;6(11):e27884
Koshman,Y. E.; Kim,T.; Chu,M.; Engman,S. J.; Iyengar,R.; Robia,S. L.; Samarel,A. M.FRNK inhibition of focal adhesion kinase-dependent signaling and migration in vascular smooth muscle cells. Arteriosclerosis, Thrombosis & Vascular Biology 2010 ;30(11):2226-2233
O'Connor,C.; Pertel,T.; Gray,S.; Robia,S. L.; Bakowska,J. C.; Luban,J.; Campbell,E. M.p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha. Journal of virology 2010 ;84(12):5997-6006
Bossuyt,J.; Despa,S.; Han,F.; Hou,Z.; Robia,S. L.; Lingrel,J. B.; Bers,D. M.Isoform specificity of the Na/K-ATPase association and regulation by phospholemman. Journal of Biological Chemistry 2009 ;284(39):26749-26757
Bhandari,D.; Robia,S. L.; Marchese,A.The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction. Molecular biology of the cell 2009 ;20(5):1324-1339
Kelly,E. M.; Hou,Z.; Bossuyt,J.; Bers,D. M.; Robia,S. L.Phospholamban oligomerization, quaternary structure, and sarco(endo)plasmic reticulum calcium ATPase binding measured by fluorescence resonance energy transfer in living cells. Journal of Biological Chemistry 2008 ;283(18):12202-12211
Hou,Z.; Kelly,E. M.; Robia,S. L.Phosphomimetic mutations increase phospholamban oligomerization and alter the structure of its regulatory complex. Journal of Biological Chemistry 2008 ;283(43):28996-29003
Robia,S. L.; Campbell,K. S.; Kelly,E. M.; Hou,Z.; Winters,D. L.; Thomas,D. D.Forster transfer recovery reveals that phospholamban exchanges slowly from pentamers but rapidly from the SERCA regulatory complex. Circulation research 2007 ;101(11):1123-1129