Vascular Biology and Hemostasis

For over 40 years, Loyola faculty in this division have participated in translational research to understand the disease process and develop innovative diagnostic methods, devices, and drugs. We seek to promote collaborative research opportunities to extend our research programs at national and international levels.

Our multi-discipline team focuses on the pathophysiological mechanisms of vascular disorders and their management via several lines of research:‚Äč

  • Venous thromboembolism
  • Acute coronary syndrome
  • Atrial fibrillation
  • Thrombotic and ischemic stroke
  • Vascular manifestations of venous disorders and sepsis associated vascular disorders
  • Cancer associated thrombosis and bleeding
  • Auto immune disease related vascular pathogenesis

 Meet the division faculty here.


Recent division activities

In April 2017, Division faculty presented 16 presentations at FASEB here in Chicago, IL:

 Author  Presentation
Zafar Siddiqui, et al. Comparative anticoagulant effects of recombinant thrombomodulin, antithrombin and unfractionated heparin, hematological implications
Ahmed Kouta, et al. Neutralization of unfractionated heparin (UFH) and bioengineered heparin dodesaccharide (12-mer) by protamine sulfate
Chris Wanderling Extrinsic and common coagulation pathway profiling in TJA patients
Elissa Finkler, et al. Profiling of inflammatory biomarkers in synovial fluid from patients undergoing primary total joint arthoplasty

Amanda Walborn, et al.

Plasma nucleosomes correlate with markers of inflammation and thrombosis in patients with sepsis-associated coagulopathy
Jawed Fareed, et al. A Polydeoxynucleotide derived drug defibrotide inhibits nucleosomes generation in whole blood. Implications in the Management of VOD.
Walter Jeske, et al. Porcine and Ovine mucosal heparins and their depolymerized derivatives are comparable in contrast to their bovine equivalents
Jeffrey Liles, et al. Correlation of nucleosomes, MMP-9, and IL-1a with Relation activation in patients with atrial fibrillation

Schuharazad Abro, et al.

Anticoagulant profiling of a generic enoxaparin and its comparison with its branded version
Olivia Bouchard, et al. Porcine and ovine mucosal heparins and their depolymerized derivatives are comparable in contrast to their bovine equivalents
Abigail Otto, et al. Elevated Circulating CD40-L in Atrial Fibrillation and its Modulation by Ablation
Nathan McClane, et al. Identification and characterization of novel hemostatic biomarkers of adverse clinical events in patients with continuous flow left ventricular assist device implants
Sayan Paria, et al. Protamine sulfate neutralization of bovine and porcine heparins: Developmental Implications
Steven Statz, et al. Angiopoietin-2 levels in the risk stratification and mortality outcome prediction of sepsis associated coagulopathy
Omar Atcho, et al.

USP referenced potency evaluation of bovine heparins utilizing currently available assays

Sandra Rodrigues, et al. Comparative analysis of inflammatory cytokines and growth factors in young and old aged normal individuals