Jose Guevara-Patino, MD, PhD

Jose Guevara-Patino, MD, PhD

Associate Professor
Surgical Research


National Institute for Medical Research, London, FR, United Kingdom
Universidad Central de Venezuela

Mutant HSP70 reverses autoimmune depigmentation in vitiligo Mosenson, J. A.; Zloza, A.; Nieland, J. D.; Garrett-Mayer, E.; Eby, J. M.; Huelsmann, E. J.; Kumar, P.; Denman, C. J.; Lacek, A. T.; Kohlhapp, F. J.; Alamiri, A.; Hughes, T.; Bines, S. D.; Kaufman, H. L.; Overbeck, A.; Mehrotra, S.; Hernandez, C.; Nishimura, M. I.; Guevara-Patino, J. A.; Le Poole, I. C., Science translational medicine

CD8(+) T cells sabotage their own memory potential through IFN-gamma-dependent modification of the IL-12/IL-15 receptor alpha axis on dendritic cells Kohlhapp, F. J.; Zloza, A.; O'Sullivan, J. A.; Moore, T. V.; Lacek, A. T.; Jagoda, M. C.; McCracken, J.; Cole, D. J.; Guevara-Patino, J. A., Journal of immunology (Baltimore, Md.: 1950)

HSP70i is a critical component of the immune response leading to vitiligo. Mosenson, J. A.; Zloza, A.; Klarquist, J.; Barfuss, A. J.; Guevara-Patino, J. A.; Poole, I. C., Pigment Cell & Melanoma Research

NKG2D signaling on CD8(+) T cells represses T-bet and rescues CD4-unhelped CD8(+) T cell memory recall but not effector responses Zloza, A.; Kohlhapp, F. J.; Lyons, G. E.; Schenkel, J. M.; Moore, T. V.; Lacek, A. T.; O'Sullivan, J. A.; Varanasi, V.; Williams, J. W.; Jagoda, M. C.; Bellavance, E. C.; Marzo, A. L.; Thomas, P. G.; Zafirova, B.; Polic, B.; Al-Harthi, L.; Sperling, A. I.; Guevara-Patino, J. A., Nature medicine

CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-beta (TGF-beta)-mediated suppression Zloza, A.; Jagoda, M. C.; Lyons, G. E.; Graves, M. C.; Kohlhapp, F. J.; O'Sullivan, J. A.; Lacek, A. T.; Nishimura, M. I.; Guevara-Patino, J. A., Cancer immunology, immunotherapy : CII

Combination of epitope-optimized DNA vaccination and passive infusion of monoclonal antibody against HER2/neu leads to breast tumor regression in miceOrlandi, F.; Guevara-Patino, J. A.; Merghoub, T.; Wolchok, J. D.; Houghton, A. N.; Gregor, P. D., Vaccine

Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-beta blockade during the perioperative period of tumor resection Bellavance, E. C.; Kohlhapp, F. J.; Zloza, A.; O'Sullivan, J. A.; McCracken, J.; Jagoda, M. C.; Lacek, A. T.; Posner, M. C.; Guevara-Patino, J. A., Journal of immunology (Baltimore, Md.: 1950)

Engagement of NK receptor NKG2D but not 2B4, results in self-reactive CD8+ T cells and autoimmune vitiligo, Zloza, A.; Lyons, G. E.; Chlewicki, L. K.; Kohlhapp, F. J.; O'Sullivan, J. A.; Lacek, A. T.; Moore, T. V.; Jagoda, M. C.; Kumar, V.; Guevara-Patino, J. A., Autoimmunity

Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)beta-mediated suppression O'Sullivan, J. A.; Zloza, A.; Kohlhapp, F. J.; Moore, T. V.; Lacek, A. T.; Dulin, N. O.; Guevara-Patino, J. A., Cancer immunology, immunotherapy : CII

Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens Cote, A. L.; Zhang, P.; O'Sullivan, J. A.; Jacobs, V. L.; Clemis, C. R.; Sakaguchi, S.; Guevara-Patino, J. A.; Turk, M. J., Journal of immunology (Baltimore, Md.: 1950)

Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodiesLazarou, M.; Guevara-Patino, J. A.; Jennings, R. M.; McIntosh, R. S.; Shi, J.; Howell, S.; Cullen, E.; Jones, T.; Adame-Gallegos, J. R.; Chappel, J. A.; McBride, J. S.; Blackman, M. J.; Holder, A. A.; Pleass, R. J.,