TNFα Selectively Activates the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Airway Smooth Muscle Cells.


Yap J, Chen X, Delmotte PF, Sieck GC.

Am J Physiol Lung Cell Mol Physiol. 2020 Jan 15. doi: 10.1152/ajplung.00212.2019. 






Endothelial Dysfunction Is Associated with Mortality and Severity of Coagulopathy in Patients with Sepsis and Disseminated Intravascular Coagulation.

Walborn A, Rondina M, Mosier M, Fareed J, Hoppensteadt D.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619852163. doi: 10.1177/1076029619852163.

PMID:   31140293

Markers of Inflammation and Infection in Sepsis and Disseminated Intravascular Coagulation.

Patel P, Walborn A, Rondina M, Fareed J, Hoppensteadt D.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619843338. doi: 10.1177/1076029619843338.

PMID: 30991817

Biomarker Profiling in Stage 5 Chronic Kidney Disease Identifies the Relationship between Angiopoietin-2 and Atrial Fibrillation.

Bontekoe J, Lee J, Bansal V, Syed M, Hoppensteadt D, Maia P, Walborn A, Liles J, Brailovsky E, Fareed J.

Clin Appl Thromb Hemost. 2018 Oct 28:1076029618808909. doi: 10.1177/1076029618808909. [Epub ahead of print]

PMID: 30370780

K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α.

Imam S, Kömürlü S, Mattick J, Selyutina A, Talley S, Eddins A, Diaz-Griffero F, Campbell EM.

J Virol. 2019 Jun 28;93(14). pii: e00558-19. doi: 10.1128/JVI.00558-19. Print 2019 Jul 15.


Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α.

Kömürlü S, Bradley M, Smolin N, Imam S, Pauszek RF 3rd, Robia SL, Millar D, Nakayama EE, Shioda T, Campbell EM.

PLoS One. 2019 Mar 19;14(3):e0212888. doi: 10.1371/journal.pone.0212888. eCollection 2019.



Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells.

Spear TT, Wang Y, Smith TW Jr., Simms PE, Garrett-Mayer E, Hellman LM, Baker BM, Nishimura MI.

Mol Ther. 2018 Feb 2. pii: S1525-0016(18)30022-4. doi: 10.1016/j.ymthe.2018.01.015.

PMID: 29503203

TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence.

Spear TT, Foley KC, Garrett-Mayer E, Nishimura MI.

J Leukoc Biol. 2018 Jan 19. doi: 10.1002/JLB.5A0817-314R.

PMID: 29350789

Age-related immune responses after burn and inhalation injury are associated with altered clinical outcomes.

Frankel JH, Boe DM, Albright JM, O'Halloran EB, Carter SR, Davis CS, Ramirez L, Burnham EL, Gamelli RL, Afshar M, Kovacs EJ.

Exp Gerontol. 2018 May;105:78-86. doi: 10.1016/j.exger.2017.10.022. Epub 2017 Oct 26.

PMID: 29080833

Biomarkers of Inflammation, Thrombogenesis, and Collagen Turnover in Patients With Atrial Fibrillation.

Jabati S, Fareed J, Liles J, Otto A, Hoppensteadt D, Bontekoe J, Phan T, Walborn A, Syed M.

Clin Appl Thromb Hemost. 2018 Jan 1:1076029618761006. doi: 10.1177/1076029618761006.

PMID: 29558818

Plasma C-reactive protein levels in bipolar depression during cyclooxygenase-2 inhibitor combination treatment.

Edberg D, Hoppensteadt D, Walborn A, Fareed J, Sinacore J, Halaris A.

J Psychiatr Res. 2018 Feb 13;102:1-7. doi: 10.1016/j.jpsychires.2018.02.004.

PMID: 29554535

Fibrinolytic Deficit and Platelet Activation in Atrial Fibrillation and Their Postablation Modulation.

Otto A, Fareed J, Liles J, Statz S, Walborn A, Rowe T, Jabati S, Hoppensteadt D, Syed MA.

Clin Appl Thromb Hemost. 2018 Jan 1:1076029617750270. doi: 10.1177/1076029617750270.

PMID: 29374968

Elevated extracellular nucleosomes and their relevance to inflammation in stage 5 chronic kidney disease.

Phan T, McMillan R, Skiadopoulos L, Walborn A, Hoppensteadt D, Fareed J, Bansal V. Int Angiol. 2018 Apr 11. doi: 10.23736/S0392-


PMID: 29644836

Cannon AR, Kuprys PV, Cobb AN, Ding X, Kothari AN, Kuo PC, Eberhardt JM, Hammer AM, Morris NL, Li X, Choudhry MA. (2018).

Alcohol enhances symptoms and propensity for infection in inflammatory bowel disease patients and a murine model of DSS-induced

colitis. J Leukoc Biol., 104(3):543-555. (PMID: 29775230)


Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.

Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa

JM, Cannova J, Zhang J, Smith ER, Crispino JD, Shilatifard A.

Cell. 2017 Jan 12;168(1-2):59-72.e13. doi: 10.1016/j.cell.2016.12.011. Epub 2017 Jan 5.

PMID: 28065413

Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling.

Li J, Volk A, Zhang J, Cannova J, Dai S, Hao C, Hu C, Sun J, Xu Y, Wei W, Breslin P, Nand S, Chen J, Kini A, Zhu J, Zhang J.

Oncotarget. 2017 Jan 31;8(5):8420-8435. doi: 10.18632/oncotarget.14220.

PMID: 28039479

Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.

Xin J, You D, Breslin P, Li J, Zhang J, Wei W, Cannova J, Volk A, Gutierrez R, Xiao Y, Ni A, Ng G, Schmidt R, Xia Z, Pan J, Chen H, Patel

MM, Kuo PC, Nand S, Kini AR, Zhang J, Chen J, Zhu J, Zhang J.

Leukemia. 2017 May;31(5):1154-1165. doi: 10.1038/leu.2016.287. Epub 2016 Oct 17.

PMID: 27748372

Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice.

Xin J, Breslin P, Wei W, Li J, Gutierrez R, Cannova J, Ni A, Ng G, Schmidt R, Chen H, Parini V, Kuo PC, Kini AR, Stiff P, Zhu J, Zhang J.

Haematologica. 2017 Feb;102(2):295-307. doi: 10.3324/haematol.2016.151514. Epub 2016 Sep 15.

PMID: 27634200

Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.

Spear TT, Wang Y, Foley KC, Murray DC, Scurti GM, Simms PE, Garrett-Mayer E, Hellman LM, Baker BM, Nishimura MI.

Cancer Immunol Immunother. 2017 Nov;66(11):1411-1424. doi: 10.1007/s00262-017-2032-9. Epub 2017 Jun 20.


HCV T Cell Receptor Chain Modifications to Enhance Expression, Pairing, and Antigen Recognition in T Cells for Adoptive Transfer.

Foley KC, Spear TT, Murray DC, Nagato K, Garrett-Mayer E, Nishimura MI.

Mol Ther Oncolytics. 2017 May 17;5:105-115. doi: 10.1016/j.omto.2017.05.004. eCollection 2017 Jun 16.

PMID: 28573185

How an alloreactive T-cell receptor achieves peptide and MHC specificity.

Wang Y, Singh NK, Spear TT, Hellman LM, Piepenbrink KH, McMahan RH, Rosen HR, Vander Kooi CW, Nishimura MI, Baker BM.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4792-E4801. doi: 10.1073/pnas.1700459114. Epub 2017 Jun 1.

PMID: 28572406

Comparative exploration of multidimensional flow cytometry software: a model approach evaluating T cell polyfunctional behavior.

Spear TT, Nishimura MI, Simms PE.

J Leukoc Biol. 2017 Aug;102(2):551-561. doi: 10.1189/jlb.6A0417-140R. Epub 2017 May 26.

PMID: 28550117

Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.

Flavin WP, Bousset L, Green ZC, Chu Y, Skarpathiotis S, Chaney MJ, Kordower JH, Melki R, Campbell EM.

Acta Neuropathol. 2017 Oct;134(4):629-653. doi: 10.1007/s00401-017-1722-x. Epub 2017 May 19.

PMID: 28527044

Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection.

Dharan A, Opp S, Abdel-Rahim O, Keceli SK, Imam S, Diaz-Griffero F, Campbell EM.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10707-E10716. doi: 10.1073/pnas.1712033114. Epub 2017 Nov 27.

PMID: 29180435

Alcohol Modulation of the Postburn Hepatic Response.

Chen MM, Carter SR, Curtis BJ, O'Halloran EB, Gamelli RL, Kovacs EJ.

J Burn Care Res. 2017 Jan/Feb;38(1):e144-e157. doi: 10.1097/BCR.0000000000000279.

PMID: 26284631

The Subventricular Zone Response to Stroke Is Not a Therapeutic Target of Anti-Nogo-A Immunotherapy.

Shepherd DJ, Tsai SY, Cappucci SP, Wu JY, Farrer RG, Kartje GL.

J Neuropathol Exp Neurol. 2017 Aug 1;76(8):683-696. doi: 10.1093/jnen/nlx050.

PMID: 28789474

FOXO3, estrogen receptor alpha, and androgen receptor impact tumor growth rate and infiltration of dendritic cell subsets differentially between male and female mice.

Thompson MG, Peiffer DS, Larson M, Navarro F, Watkins SK.

Cancer Immunol Immunother. 2017 May;66(5):615-625. doi: 10.1007/s00262-017-1972-4. Epub 2017 Feb 22.

PMID: 28229217

Postoperative Changes in the Systemic Inflammatory Milieu in Older Surgical Patients.

Shih L, Guler N, Syed D, Hopkins W, McComas KN, Walborn A, Hoppensteadt D, Fareed J, Rondina MT.

Clin Appl Thromb Hemost. 2017 Jan 1:1076029617747412. doi: 10.1177/1076029617747412.

PMID: 29258393

Biomarker profiling of plasma samples utilizing RANDOX biochip array technology.

Saluk J, Hoppensteadt D, Syed D, Liles J, Abro S, Walborn A, Bansal V, Fareed J.

Int Angiol. 2017 Dec;36(6):499-504. doi: 10.23736/S0392-9590.17.03854-8. Epub 2017 Jun 9.

PMID: 28598140

Biomarker Profile of Sepsis-Associated Coagulopathy Using Biochip Assay for Inflammatory Cytokines.

Walborn A, Hoppensteadt D, Syed D, Mosier M, Fareed J.

Clin Appl Thromb Hemost. 2017 Jan 1:1076029617709084. doi: 10.1177/1076029617709084.

PMID: 28514870

Modulation of Interleukins in Sepsis-Associated Clotting Disorders: Interplay With Hemostatic Derangement.

Low C, Syed D, Khan D, Tetik S, Walborn A, Hoppensteadt D, Mosier M, Fareed J.

Clin Appl Thromb Hemost. 2017 Jan;23(1):34-39. Epub 2016 Jul 21.

PMID: 27449508

Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor.

Zak TJ, Koshman YE, Samarel AM, Robia SL.

Biochemistry. 2017 Sep 5;56(35):4722-4731. doi: 10.1021/acs.biochem.7b00616. Epub 2017 Aug 23.

PMID: 28782937

Improved functional outcome after chronic stroke with delayed anti-Nogo-A therapy: A clinically relevant intention-to-treat analysis.

Podraza KM, Mehta Y, Husak VA, Lippmann E, O'Brien TE, Kartje GL, Tsai SY.

J Cereb Blood Flow Metab. 2017 Jan 1:271678X17730994. doi: 10.1177/0271678X17730994.

PMID: 28952904


Strategies to genetically engineer T cells for cancer immunotherapy.

Spear TT, Nagato K, Nishimura MI.

Cancer Immunol Immunother. 2016 Jun;65(6):631-49. doi: 10.1007/s00262-016-1842-5. Epub 2016 May 2.

PMID: 27138532

Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability.

Spear TT, Riley TP, Lyons GE, Callender GG, Roszkowski JJ, Wang Y, Simms PE, Scurti GM, Foley KC, Murray DC, Hellman LM, McMahan RH, Iwashima M, Garrett-Mayer E, Rosen HR, Baker BM, Nishimura MI.

J Leukoc Biol. 2016 Sep;100(3):545-57. doi: 10.1189/jlb.2A1215-561R. Epub 2016 Feb 26.

PMID: 26921345

Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes.

Hellman LM, Yin L, Wang Y, Blevins SJ, Riley TP, Belden OS, Spear TT, Nishimura MI, Stern LJ, Baker BM.

J Immunol Methods. 2016 May;432:95-101. doi: 10.1016/j.jim.2016.02.016. Epub 2016 Feb 18.

PMID: 26906089

How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire.

Blevins SJ, Pierce BG, Singh NK, Riley TP, Wang Y, Spear TT, Nishimura MI, Weng Z, Baker BM.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1276-85. doi: 10.1073/pnas.1522069113. Epub 2016 Feb 16.

PMID: 26884163

TCR gene-modified T cells can efficiently treat established hepatitis C-associated hepatocellular carcinoma tumors.

Spear TT, Callender GG, Roszkowski JJ, Moxley KM, Simms PE, Foley KC, Murray DC, Scurti GM, Li M, Thomas JT, Langerman A, Garrett-Mayer E, Zhang Y, Nishimura MI.

Cancer Immunol Immunother. 2016 Mar;65(3):293-304. doi: 10.1007/s00262-016-1800-2. Epub 2016 Feb 3.

PMID: 26842125

Loss of Bin1 Promotes the Propagation of Tau Pathology.

Calafate S, Flavin W, Verstreken P, Moechars D.

Cell Rep. 2016 Oct 18;17(4):931-940. doi: 10.1016/j.celrep.2016.09.063.

PMID: 27760323

Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization.

Samuel F, Flavin WP, Iqbal S, Pacelli C, Sri Renganathan SD, Trudeau LE, Campbell EM, Fraser PE, Tandon A.

J Biol Chem. 2016 Feb 26;291(9):4374-85. doi: 10.1074/jbc.M115.705095. Epub 2015 Dec 30.

PMID: 26719332

TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction.

Imam S, Talley S, Nelson RS, Dharan A, O'Connor C, Hope TJ, Campbell EM.

J Virol. 2016 Jan 13;90(7):3400-10. doi: 10.1128/JVI.03033-15.

PMID: 26764007

Alcohol and lung injury and immunity.

Yeligar SM, Chen MM, Kovacs EJ, Sisson JH, Burnham EL, Brown LA.

Alcohol. 2016 Sep;55:51-59. doi: 10.1016/j.alcohol.2016.08.005. Epub 2016 Sep 16.

PMID: 27788778

Kupffer Cell p38 Mitogen-Activated Protein Kinase Signaling Drives Postburn Hepatic Damage and Pulmonary Inflammation When Alcohol Intoxication Precedes Burn Injury.

Chen MM, O'Halloran EB, Shults JA, Kovacs EJ.

Crit Care Med. 2016 Oct;44(10):e973-9. doi: 10.1097/CCM.0000000000001817.

PMID: 27322363

Alveolar macrophage inflammatory mediator expression is elevated in the setting of alcohol use disorders.

O'Halloran EB, Curtis BJ, Afshar M, Chen MM, Kovacs EJ, Burnham EL.

Alcohol. 2016 Feb;50:43-50. doi: 10.1016/j.alcohol.2015.11.003. Epub 2015 Nov 24.

PMID: 26781212

Neutrophil Accumulation in the Small Intestine Contributes to Local Tissue Destruction Following Combined Radiation and Burn Injury.

Carter SR, Chen MM, Palmer JL, Wang L, Ramirez L, Plackett TP, Gamelli RL, Kovacs EJ.

J Burn Care Res. 2016 Mar-Apr;37(2):97-105. doi: 10.1097/BCR.0000000000000220.


Ethanol intoxication prolongs post-burn pulmonary inflammation: role of alveolar macrophages.

Shults JA, Curtis BJ, Boe DM, Ramirez L, Kovacs EJ.

J Leukoc Biol. 2016 Nov;100(5):1037-1045. Epub 2016 Aug 16.

PMID: 27531926

Advanced Age Alters Monocyte and Macrophage Responses.

Albright JM, Dunn RC, Shults JA, Boe DM, Afshar M, Kovacs EJ.

Antioxid Redox Signal. 2016 Nov 20;25(15):805-815. Epub 2016 Aug 3.


Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats.

Shepherd DJ, Tsai SY, O'Brien TE, Farrer RG, Kartje GL.

Front Neurosci. 2016 Oct 18;10:467. eCollection 2016.

PMID: 27803646

Induction of antitoxin responses in Clostridium-difficile-infected patients compared to healthy blood donors.

von Eichel-Streiber A, Paik W, Knight K, Gisch K, Nadjafi K, Decker C, Bosnjak O, Cheknis A, Johnson S, von Eichel-Streiber C.

Anaerobe. 2016 Oct;41:91-103. doi: 10.1016/j.anaerobe.2016.07.001. Epub 2016 Jul 15.

PMID: 27427464

Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer.

Blackwell DJ, Zak TJ, Robia SL.

Biophys J. 2016 Sep 20;111(6):1192-1202. doi: 10.1016/j.bpj.2016.08.005.

PMID: 27653478

Factors Influencing the Management of Unruptured Intracranial Aneurysms.

Gillani RL, Podraza KM, Luthra N, Origitano TC, Schneck MJ.

Cureus. 2016 May 4;8(5):e601. doi: 10.7759/cureus.601.

PMID: 27335713

Tan, Hon Liang, Yap JQ, Qian Q. “Acute Kidney Injury: Tubular Markers and Risk for Chronic Kidney Disease and End-Stage Kidney Failure.” Blood Purification, vol. 41, no. 1-3, 2016, pp. 144–150., doi:10.1159/000441269.

Li, Heng, Sun SR, Yap JQ, Chen JH, Qian Q.. “0.9% Saline Is Neither Normal nor Physiological.” Journal of Zhejiang University-SCIENCE B, vol. 17, no. 3, 2016, pp. 181–187., doi:10.1631/jzus.b1500201.


Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases.

Cannova J, Breslin S J P, Zhang J.

Front Med. 2015 Sep;9(3):288-303. doi: 10.1007/s11684-015-0412-0. Epub 2015 Aug 22. Review.

PMID: 26297301 FYNagling divergent adhesive functions for Fyn in keratinocytes.

Fenton SE, Denning MF.

Exp Dermatol. 2015 Feb;24(2):81-5. doi: 10.1111/exd.12485. Epub 2014 Nov 11.

PMID: 24980626

Targeting Fyn in Ras-transformed cells induces F-actin to promote adherens junction-mediated cell-cell adhesion.

Fenton SE, Hutchens KA, Denning MF.

Mol Carcinog. 2015 Oct;54(10):1181-93. doi: 10.1002/mc.22190. Epub 2014 Jun 29.

PMID: 4976598

Impaired respiratory function and heightened pulmonary inflammation in episodic binge ethanol intoxication and burn injury.

Shults JA, Curtis BJ, Chen MM, O'Halloran EB, Ramirez L, Kovacs EJ.

Alcohol. 2015 Nov;49(7):713-20. doi: 10.1016/j.alcohol.2015.06.006. Epub 2015 Aug 14.

PMID: 26364264

Extracellular traps and macrophages: new roles for the versatile phagocyte.

Boe DM, Curtis BJ, Chen MM, Ippolito JA, Kovacs EJ.

J Leukoc Biol. 2015 Jun;97(6):1023-35. doi: 10.1189/jlb.4RI1014-521R. Epub 2015 Apr 15.

PMID: 25877927

Alcohol and inflammatory responses: summary of the 2013 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Morris NL, Ippolito JA, Curtis BJ, Chen MM, Friedman SL, Hines IN, Haddad GE, Chang SL, Brown LA, Waldschmidt TJ, Mandrekar P, Kovacs EJ, Choudhry MA.

Alcohol. 2015 Feb;49(1):1-6. doi: 10.1016/j.alcohol.2014.07.018. Epub 2014 Nov 3.

PMID: 25468277

Alcohol potentiates postburn remote organ damage through shifts in fluid compartments mediated by bradykinin.

Chen MM, O'Halloran EB, Ippolito JA, Choudhry MA, Kovacs EJ.

Shock. 2015 Jan;43(1):80-4. doi: 10.1097/SHK.0000000000000265.

PMID: 25243425

Intestine immune homeostasis after alcohol and burn injury.

Li X, Hammer AM, Rendon JL, Choudhry MA.

Shock. 2015 Jun;43(6):540-8. doi: 10.1097/SHK.0000000000000353.

PMID: 25692258

CCL22 to Activate Treg Migration and Suppress Depigmentation in Vitiligo.

Eby JM, Kang HK, Tully ST, Bindeman WE, Peiffer DS, Chatterjee S, Mehrotra S, Le Poole IC.

J Invest Dermatol. 2015 Jun;135(6):1574-1580. doi: 10.1038/jid.2015.26. Epub 2015 Jan 9.

PMID: 25634358

Experimental Approaches to Tissue Injury and Repair in Advanced Age.

Brubaker AL, Carter SR, Kovacs EJ.

Methods Mol Biol. 2015;1343:35-51. doi: 10.1007/978-1-4939-2963-4_4.

PMID: 26420707


Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region.

Sastri J, Johnsen L, Smolin N, Imam S, Mukherjee S, Lukic Z, Brandariz-Nuñez A, Robia SL, Diaz-Griffero F, Wiethoff C, Campbell EM.

J Virol. 2014 Aug;88(16):8911-23. doi: 10.1128/JVI.01134-14. Epub 2014 May 28.

PMID: 24872590

The systemic immune response to trauma: an overview of pathophysiology and treatment.

Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P, Lilford RJ.

Lancet. 2014 Oct 18;384(9952):1455-65. doi: 10.1016/S0140-6736(14)60687-5. Epub 2014 Oct 17. Review.

PMID: 25390327

Street smarts of science for students.

Chen MM, Zahs A, Chang SL, Kovacs EJ.

Nat Immunol. 2014 Nov;15(11):997-9. doi: 10.1038/ni.2989.

PMID: 25329178

An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice.

Chen MM, Zahs A, Brown MM, Ramirez L, Turner JR, Choudhry MA, Kovacs EJ.

Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G711-8. doi: 10.1152/ajpgi.00185.2014. Epub 2014 Aug 7.

PMID: 25104501

Age-related differences in the neutrophil response to pulmonary pseudomonas infection.

Chen MM, Palmer JL, Plackett TP, Deburghgraeve CR, Kovacs EJ.

Exp Gerontol. 2014 Jun;54:42-6. doi: 10.1016/j.exger.2013.12.010. Epub 2014 Jan 5.

PMID: 24398045

T cell IFN-γ suppression following alcohol and burn injury is independent of miRNA155.

Li X, Rendon JL, Choudhry MA.

PLoS One. 2014 Aug 15;9(8):e105314. doi: 10.1371/journal.pone.0105314. eCollection 2014.

PMID: 25126745

The role of aryl hydrocarbon receptor in interleukin-23-dependent restoration of interleukin-22 following ethanol exposure and burn injury.

Rendon JL, Li X, Brubaker AL, Kovacs EJ, Gamelli RL, Choudhry MA.

Ann Surg. 2014 Mar;259(3):582-90. doi: 10.1097/SLA.0b013e3182a626f2.

PMID: 23989051

Episodic binge ethanol exposure impairs murine macrophage infiltration and delays wound closure by promoting defects in early innate immune responses.

Curtis BJ, Hlavin S, Brubaker AL, Kovacs EJ, Radek KA.

Alcohol Clin Exp Res. 2014 May;38(5):1347-55. doi: 10.1111/acer.12369. Epub 2014 Apr 1.

PMID: 24689549

The role of aryl hydrocarbon receptor in interleukin-23-dependent restoration of interleukin-22 following ethanol exposure and burn injury.

Rendon JL, Li X, Brubaker AL, Kovacs EJ, Gamelli RL, Choudhry MA.

Ann Surg. 2014 Mar;259(3):582-90. doi: 10.1097/SLA.0b013e3182a626f2.

PMID: 23989051


Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia.

Risner LE, Kuntimaddi A, Lokken AA, Achille NJ, Birch NW, Schoenfelt K, Bushweller JH, Zeleznik-Le NJ.

J Biol Chem. 2013 Oct 11;288(41):29901-10. doi: 10.1074/jbc.M113.474858. Epub 2013 Aug 29.

PMID: 23990460

Intoxication by intraperitoneal injection or oral gavage equally potentiates postburn organ damage and inflammation.

Chen MM, Palmer JL, Ippolito JA, Curtis BJ, Choudhry MA, Kovacs EJ.

Mediators Inflamm. 2013;2013:971481. doi: 10.1155/2013/971481. Epub 2013 Nov 28.

PMID: 24379525

The aging lung.

Lowery EM, Brubaker AL, Kuhlmann E, Kovacs EJ.

Clin Interv Aging. 2013;8:1489-96. doi: 10.2147/CIA.S51152. Epub 2013 Nov 6. Review.

PMID: 24235821

Combined radiation and burn injury results in exaggerated early pulmonary inflammation.

Palmer JL, Deburghgraeve CR, Bird MD, Hauer-Jensen M, Chen MM, Yong S, Kovacs EJ.

Radiat Res. 2013 Sep;180(3):276-83. doi: 10.1667/RR3104.1. Epub 2013 Jul 30.

PMID: 23899376

Pulmonary inflammation after ethanol exposure and burn injury is attenuated in the absence of IL-6.

Chen MM, Bird MD, Zahs A, Deburghgraeve C, Posnik B, Davis CS, Kovacs EJ.

Alcohol. 2013 May;47(3):223-9. doi: 10.1016/j.alcohol.2013.01.004. Epub 2013 Feb 23.

PMID: 23462222

Noninvasive measurement of intestinal inflammation after burn injury.

Sigman M, Conrad P, Rendon JL, Akhtar S, Eberhardt J, Gamelli RL, Choudhry MA.

J Burn Care Res. 2013 Nov-Dec;34(6):633-8. doi: 10.1097/BCR.0b013e318280e2f8.

PMID: 23511286

Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age.

Brubaker AL, Rendon JL, Ramirez L, Choudhry MA, Kovacs EJ.

J Immunol. 2013 Feb 15;190(4):1746-57. doi: 10.4049/jimmunol.1201213. Epub 2013 Jan 14.

PMID: 23319733

Interleukin-22 modulates gut epithelial and immune barrier functions following acute alcohol exposure and burn injury.

Rendon JL, Li X, Akhtar S, Choudhry MA.

Shock. 2013 Jan;39(1):11-8. doi: 10.1097/SHK.0b013e3182749f96.

PMID: 23143063

Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis.

Freeman D, Cedillos R, Choyke S, Lukic Z, McGuire K, Marvin S, Burrage AM, Sudholt S, Rana A, O'Connor C, Wiethoff CM, Campbell EM.

PLoS One. 2013 Apr 25;8(4):e62143. doi: 10.1371/journal.pone.0062143. Print 2013.

PMID: 23634225

Increased expression of secreted frizzled-related protein-1 and microtubule-associated protein light chain 3 in keratoconus.

Iqbal O, Fisher G, Vira S, Syed D, Sadeghi N, Freeman D, Campbell E, Sugar J, Feder R, Fareed J, Bouchard C.

Cornea. 2013 May;32(5):702-7. doi: 10.1097/ICO.0b013e318282987a.

PMID: 23449484

G-CSF enhances resolution of Staphylococcus aureus wound infection in an age-dependent manner.

Brubaker AL, Kovacs EJ.

Shock. 2013 Oct;40(4):327-33. doi: 10.1097/SHK.0b013e3182a43651.

PMID: 23856924

Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age.

Brubaker AL, Rendon JL, Ramirez L, Choudhry MA, Kovacs EJ.

J Immunol. 2013 Feb 15;190(4):1746-57. doi: 10.4049/jimmunol.1201213. Epub 2013 Jan 14.

PMID: 23319733