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David J. Leehey
Primary Department
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Kidney Stones
Kidney Disorders
Diabetic Kidney Disease
High Blood Pressure
Loyola Hospital
Loyola Outpatient Center
Loyola Center for Dialysis on Roosevelt
American Board of Internal Medicine Subspecialty Nephrology
American Board of Internal Medicine
Medical School
Boston University School of Medicine
Michael Reese Hospital, Internal Medicine: General
University of Chicago Hospitals and Clinics, Internal Medicine: Nephrology
Classical Music
Kramer,H.; Boucher,R. E.; Leehey,D.; Fried,L.; Wei,G.; Greene,T.; Rosas,S. E.; Cooper,R.; Cao,G.; Beddhu,S.Increasing Mortality in Adults With Diabetes and Low Estimated Glomerular Filtration Rate in the Absence of Albuminuria Diabetes care 2018 ;41(4):775-781
Small,C.; Kramer,H. J.; Griffin,K. A.; Vellanki,K.; Leehey,D. J.; Bansal,V. K.; Markossian,T. W.Non-dialysis dependent chronic kidney disease is associated with high total and out-of-pocket healthcare expenditures BMC Nephrology 2017 ;18(1):3-016-0432-2
Markossian,T.; Burge,N.; Ling,B.; Schneider,J.; Pacold,I.; Bansal,V.; Leehey,D.; Stroupe,K.; Chang,A.; Kramer,H.Controversies Regarding Lipid Management and Statin Use for Cardiovascular Risk Reduction in Patients With CKD American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 2016 ; :
Patel,M.; Vellanki,K.; Leehey,D. J.; Bansal,V. K.; Brubaker,L.; Flanigan,R.; Koval,J.; Wadhwa,A.; Balasubramanian,N.; Sandhu,J.; Kramer,H.Urinary incontinence and diuretic avoidance among adults with chronic kidney disease International Urology and Nephrology 2016 ; :
Williams,R. C.; Elston,R. C.; Kumar,P.; Knowler,W. C.; Abboud,H. E.; Adler,S.; Bowden,D. W.; Divers,J.; Freedman,B. I.; Igo,R. P.,Jr; Ipp,E.; Iyengar,S. K.; Kimmel,P. L.; Klag,M. J.; Kohn,O.; Langefeld,C. D.; Leehey,D. J.; Nelson,R. G.; Nicholas,S. B.; Pahl,M. V.; Parekh,R. S.; Rotter,J. I.; Schelling,J. R.; Sedor,J. R.; Shah,V. O.; Smith,M. W.; Taylor,K. D.; Thameem,F.; Thornley-Brown,D.; Winkler,C. A.; Guo,X.; Zager,P.; Hanson,R. L.; FIND Research GroupSelecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) BMC genomics 2016 ;17(1):325-016-2654-x
Leehey,D. J.; Zhang,J. H.; Emanuele,N. V.; Whaley-Connell,A.; Palevsky,P. M.; Reilly,R. F.; Guarino,P.; Fried,L. F.; VA NEPHRON-D Study GroupBP and Renal Outcomes in Diabetic Kidney Disease: The Veterans Affairs Nephropathy in Diabetes Trial Clinical journal of the American Society of Nephrology : CJASN 2015 ;10(12):2159-2169
Alhosaini,M.; Leehey,D. J.Magnesium and Dialysis: The Neglected Cation American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 2015 ;66(3):523-531
Garrity,B. H.; Kramer,H.; Vellanki,K.; Leehey,D.; Brown,J.; Shoham,D. A.Time trends in the association of ESRD incidence with area-level poverty in the US population Hemodialysis international.International Symposium on Home Hemodialysis 2015 ; :
Iyengar,S. K.; Sedor,J. R.; Freedman,B. I.; Kao,W. H.; Kretzler,M.; Keller,B. J.; Abboud,H. E.; Adler,S. G.; Best,L. G.; Bowden,D. W.; Burlock,A.; Chen,Y. D.; Cole,S. A.; Comeau,M. E.; Curtis,J. M.; Divers,J.; Drechsler,C.; Duggirala,R.; Elston,R. C.; Guo,X.; Huang,H.; Hoffmann,M. M.; Howard,B. V.; Ipp,E.; Kimmel,P. L.; Klag,M. J.; Knowler,W. C.; Kohn,O. F.; Leak,T. S.; Leehey,D. J.; Li,M.; Malhotra,A.; Marz,W.; Nair,V.; Nelson,R. G.; Nicholas,S. B.; O'Brien,S. J.; Pahl,M. V.; Parekh,R. S.; Pezzolesi,M. G.; Rasooly,R. S.; Rotimi,C. N.; Rotter,J. I.; Schelling,J. R.; Seldin,M. F.; Shah,V. O.; Smiles,A. M.; Smith,M. W.; Taylor,K. D.; Thameem,F.; Thornley-Brown,D. P.; Truitt,B. J.; Wanner,C.; Weil,E. J.; Winkler,C. A.; Zager,P. G.; Igo,R. P.,Jr; Hanson,R. L.; Langefeld,C. D.; Family Investigation of Nephropathy and Diabetes (FIND)Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND) PLoS Genetics 2015 ;11(8):e1005352
Alhosaini,M.; Leehey,D.; Kramer,H.Bariatric surgery: the solution to a big problem? American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 2014 ;64(3):332-334
Alhosaini,M.; Walter,J. S.; Singh,S.; Dieter,R. S.; Hsieh,A.; Leehey,D. J.Hypomagnesemia in Hemodialysis Patients: Role of Proton Pump Inhibitors American Journal of Nephrology 2014 ;39(3):204-209
Hammond,K.; You,D.; Collins,E. G.; Leehey,D. J.; Laghi,F.Life-threatening hypokalemia following rapid correction of respiratory acidosis Heart & lung : the journal of critical care 2013 ;42(4):287-289
Fried,L. F.; Emanuele,N.; Zhang,J. H.; Brophy,M.; Conner,T. A.; Duckworth,W.; Leehey,D. J.; McCullough,P. A.; O'Connor,T.; Palevsky,P. M.; Reilly,R. F.; Seliger,S. L.; Warren,S. R.; Watnick,S.; Peduzzi,P.; Guarino,P.; VA NEPHRON-D InvestigatorsCombined Angiotensin inhibition for the treatment of diabetic nephropathy The New England journal of medicine 2013 ;369(20):1892-1903
Herek,J. I.; FitzGerald,M. P.; Mohindra,M.; Wickman,C.; Leehey,D. J.; Bidani,A. K.; Griffin,K. A.Solute and water excretion patterns in patients with nocturnal polyuria International Journal of Nephrology & Urology 2010 ;2(4):526-531
Leehey,D. J.; Casini,T.; Massey,D.Remission of membranous nephropathy after therapy with astragalus membranaceus American Journal of Kidney Diseases 2010 ;55(4):772-772
Leehey,D. J.; Moinuddin,I.; Bast,J. P.; Qureshi,S.; Jelinek,C. S.; Cooper,C.; Edwards,L. C.; Smith,B. M.; Collins,E. G.Aerobic exercise in obese diabetic patients with chronic kidney disease: a randomized and controlled pilot study. Cardiovascular Diabetology 2009 ;8:62
Rao,C. Y.; Pachucki,C.; Cali,S.; Santhiraj,M.; Krankoski,K. L.; Noble-Wang,J. A.; Leehey,D. J.; Popli,S.; Brandt,M. E.; Lindsley,M. D.; Fridkin,S. K.; Arduino,M. J.Contaminated product water as the source of Phialemonium curvatum bloodstream infection among patients undergoing hemodialysis. Infection Control & Hospital Epidemiology 2009 ;30(9):840-847
Mehta,S. D.; Leehey,D. J.Disparity in utilization of combined kidney-liver transplantation in the United States Clinical transplantation 2009 ;23(6):938-942
Singh,R.; Choubey,D.; Chen,J.; Leehey,D. J.Inhibition of intracellular angiotensin II formation blocks high glucose effect on mesangial matrix. Regulatory peptides 2009 ;158(1-3):103-109
Kramer,H.; Tuttle,K. R.; Leehey,D.; Luke,A.; Durazo-Arvizu,R.; Shoham,D.; Cooper,R.; Beddhu,S.Obesity management in adults with CKD American Journal of Kidney Diseases 2009 ;53(1):151-165
Malhotra,A.; Igo,R. P.,Jr; Thameem,F.; Kao,W. H.; Abboud,H. E.; Adler,S. G.; Arar,N. H.; Bowden,D. W.; Duggirala,R.; Freedman,B. I.; Goddard,K. A.; Ipp,E.; Iyengar,S. K.; Kimmel,P. L.; Knowler,W. C.; Kohn,O.; Leehey,D. J.; Meoni,L. A.; Nelson,R. G.; Nicholas,S. B.; Parekh,R. S.; Rich,S. S.; Chen,Y. D.; Saad,M. F.; Scavini,M.; Schelling,J. R.; Sedor,J. R.; Shah,V. O.; Taylor,K. D.; Thornley-Brown,D.; Zager,P. G.; Horvath,A.; Hanson,R. L.Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. Diabetes/Metabolism Research Reviews 2009 ;25(8):740-747
Kao,W. H.; Klag,M. J.; Meoni,L. A.; Reich,D.; Berthier-Schaad,Y.; Li,M.; Coresh,J.; Patterson,N.; Tandon,A.; Powe,N. R.; Fink,N. E.; Sadler,J. H.; Weir,M. R.; Abboud,H. E.; Adler,S. G.; Divers,J.; Iyengar,S. K.; Freedman,B. I.; Kimmel,P. L.; Knowler,W. C.; Kohn,O. F.; Kramp,K.; Leehey,D. J.; Nicholas,S. B.; Pahl,M. V.; Schelling,J. R.; Sedor,J. R.; Thornley-Brown,D.; Winkler,C. A.; Smith,M. W.; Parekh,R. S.MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nature genetics 2008 ;40(10):1185-1192
Leehey,D. J.; Singh,A. K.; Bast,J. P.; Sethupathi,P.; Singh,R.Glomerular renin angiotensin system in streptozotocin diabetic and Zucker diabetic fatty rats. Translational Research: The Journal Of Laboratory & Clinical Medicine 2008 ;151(4):208-216
Levey,S. A.; Bajwa,R. S.; Picken,M. M.; Clark,J. I.; Barton,K.; Leehey,D. J.Thrombotic microangiopathy associated with sunitinib, a VEGF inhibitor, in a patient with factor V Leiden mutation. NDT Plus 2008 ;3:154-156
Moinuddin,I.; Leehey,D. J.A comparison of aerobic exercise and resistance training in patients with and without chronic kidney disease Advances in Chronic Kidney Disease 2008 ;15(1):83-96
Singh,R.; Leehey,D. J.Effect of ACE inhibitors on angiotensin II in rat mesangial cells cultured in high glucose. Biochemical & Biophysical Research Communications 2007 ;357(4):1040-1045
Ahmed,M. S.; Hou,S. H.; Battaglia,M. C.; Picken,M. M.; Leehey,D. J.Treatment of idiopathic membranous nephropathy with the herb Astragalus membranaceus. American Journal of Kidney Diseases 2007 ;50(6):1028-1032
Kapur,U.; Barton,K.; Fresco,R.; Leehey,D. J.; Picken,M. M.Expanding the pathologic spectrum of immunoglobulin light chain proximal tubulopathy. Archives of Pathology & Laboratory Medicine 2007 ;131(9):1368-1372
Leischner,M. P.; Naratadam,G. O.; Hou,S. H.; Singh,A. K.; Leehey,D. J.Evaluation of proteinuria in healthy living kidney donor candidates. Transplantation proceedings 2006 ;38(9):2796-2797
Marcic,S. M.; Kammeyer,P. L.; Aneziokoro,C.; Bartnicki,L.; Yong,S.; Leehey,D. J."Culture-negative" peritonitis due to Histoplasma capsulatum. Nephrology Dialysis Transplantation 2006 ;21(10):3002
Agarwal,R.; Rizkala,A. R.; Bastani,B.; Kaskas,M. O.; Leehey,D. J.; Besarab,A.A randomized controlled trial of oral versus intravenous iron in chronic kidney disease. American Journal of Nephrology 2006 ;26(5):445-454
West,B. L.; Picken,M. M.; Leehey,D. J.Albuminuria in acute tubular necrosis. Nephrology Dialysis Transplantation 2006 ;21(10):2953-2956
Singh,R.; Singh,A. K.; Leehey,D. J.A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli. American Journal of Physiology - Renal Physiology 2005 ;288(6):F1183-90
Leehey,D. J.; Isreb,M. A.; Marcic,S.; Singh,A. K.; Singh,R.Effect of high glucose on superoxide in human mesangial cells: role of angiotensin II. Nephron.Experimental Nephrology 2005 ;100(1):e46-53
Leehey,D. J.; Kramer,H. J.; Daoud,T. M.; Chatha,M. P.; Isreb,M. A.Progression of kidney disease in type 2 diabetes - beyond blood pressure control: an observational study. BMC Nephrology 2005 ;6(1):8
Leehey,D. J.; Palubiak,D. J.; Chebrolu,S.; Agarwal,R.Sodium ferric gluconate causes oxidative stress but not acute renal injury in patients with chronic kidney disease: a pilot study. Nephrology Dialysis Transplantation 2005 ;20(1):135-140
Ahmed,M. S.; Patel,A.; Borge,M. A.; Picken,M. M.; Leehey,D. J.Simultaneous transjugular renal biopsy and hemodialysis catheter placement in patients with ARF. American Journal of Kidney Diseases 2004 ;44(3):429-436
Ulozas,E.; Chebrolu,S. B.; Shanaah,A.; Daoud,T. M.; Leehey,D. J.; Ing,T. S.Symptomatic hypocalcemia due to the inadvertent use of a calcium-free hemodialysate. Artificial Organs 2004 ;28(2):229-231
Singh,R.; Singh,A. K.; Alavi,N.; Leehey,D. J.Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose. Journal of the American Society of Nephrology 2003 ;14(4):873-880
Wright,K.; Popli,S.; Gandhi,V. C.; Lentino,J. R.; Reyes,C. V.; Leehey,D. J.Paecilomyces peritonitis: case report and review of the literature Clinical nephrology 2003 ;59(4):305-310
Sam,R.; Sahani,M.; Ulozas,E.; Leehey,D. J.; Ing,T. S.; Gandhi,V. C.Utility of a peritoneal dialysis leukocyte test strip in the diagnosis of peritonitis. Artificial Organs 2002 ;26(6):546-548
Sam,R.; Leehey,D. J.; Picken,M. M.; Borge,M. A.; Yetter,E. M.; Ing,T. S.; Van Thiel,D. H.Transjugular renal biopsy in patients with liver disease American Journal of Kidney Diseases 2001 ;37(6):1144-1151
Sahani,M. M.; Brennan,J. F.; Nwakanma,C.; Chow,M. T.; Ing,T. S.; Leehey,D. J.Metabolic alkalosis in a hemodialysis patient after ingestion of a large amount of an antacid medication. Artificial Organs 2001 ;25(4):313-315
Singh,R.; Song,R. H.; Alavi,N.; Pegoraro,A. A.; Singh,A. K.; Leehey,D. J.High glucose decreases matrix metalloproteinase-2 activity in rat mesangial cells via transforming growth factor-beta1. Experimental nephrology 2001 ;9(4):249-257
Sahani,M. M.; Mukhtar,K. N.; Boorgu,R.; Leehey,D. J.; Popli,S.; Ing,T. S.Tissue plasminogen activator can effectively declot peritoneal dialysis catheters. American Journal of Kidney Diseases 2000 ;36(3):675
Sam,R.; Leehey,D. J.Improved graft survival after renal transplantation in the United States, 1988 to 1996 New England Journal of Medicine 2000 ;342(24):1837-1838
Leehey,D. J.; Singh,A. K.; Alavi,N.; Singh,R.Role of angiotensin II in diabetic nephropathy Kidney International - Supplement 2000 ;77:S93-8
Gatchalian,R. A.; Leehey,D. J.Mortality among patients on dialysis, patients on dialysis awaiting transplantation, and transplant recipients New England Journal of Medicine 2000 ;342(12):893-894
Gatchalian,R. A.; Popli,A.; Ejaz,A. A.; Leehey,D. J.; Kjellstrand,C. M.; Ing,T. S.Management of hypophosphatemia induced by high-flux hemodiafiltration for the treatment of vancomycin toxicity: intravenous phosphorus therapy versus use of a phosphorus-enriched dialysate. American Journal of Kidney Diseases 2000 ;36(6):1262-1266