- Profile Image
- Name
- Harel Dahari
- Degree
- Ph.D.
- Rank
- Associate Professor
- Primary Department
- Medicine
- Publications
- Shekhtman, L; Cotler, SJ; Degasperi, E; Anolli, MP; Uceda Renteria, SC; Sambarino, D; Borghi, M; Perbellini, R; Facchetti, F; Ceriotti, F; Lampertico, P; Dahari, H Modelling HDV kinetics under the entry inhibitor bulevirtide suggests the existence of two HDV-infected cell populations. JHEP reports : innovation in hepatology ; 6 2
- Tatara, E; Lin, Q; Ozik, J; Kolak, M; Collier, N; Halpern, D; Anselin, L; Dahari, H; Boodram, B; Schneider, J Spatial inequities in access to medications for treatment of opioid use disorder highlight scarcity of methadone providers under counterfactual scenarios. medRxiv : the preprint server for health sciences ;
- Shekhtman, L; Duehren, S; Etzion, O; Cotler, SJ; Dahari, H Hepatitis D Virus and HBsAg Dynamics in the era of new Antiviral Treatments. Current gastroenterology reports ;
- Hershkovich, L; Shekhtman, L; Bazinet, M; Pântea, V; Placinta, G; Cotler, SJ; Vaillant, A; Dahari, H Rapid monophasic HBsAg decline during nucleic-acid polymer-based therapy predicts functional cure. Hepatology communications ; 7 8
- Sausen, DG; Shechter, O; Gallo, ES; Dahari, H; Borenstein, R Herpes Simplex Virus, Human Papillomavirus, and Cervical Cancer: Overview, Relationship, and Treatment Implications. Cancers ; 15 14
- Hailegiorgis, A; Ishida, Y; Collier, N; Imamura, M; Shi, Z; Reinharz, V; Tsuge, M; Barash, D; Hiraga, N; Yokomichi, H; Tateno, C; Ozik, J; Uprichard, SL; Chayama, K; Dahari, H Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics. PLoS computational biology ; 19 8
- Maya, S; Hershkovich, L; Cardozo-Ojeda, EF; Shirvani-Dastgerdi, E; Srinivas, J; Shekhtman, L; Uprichard, SL; Berneshawi, AR; Cafiero, TR; Dahari, H; Ploss, A Hepatitis delta virus RNA decline post-inoculation in human NTCP transgenic mice is biphasic. mBio ;
- Kushner, T; Nyabanga, CT; Cotler, SJ; Etzion, O; Dahari, H Modeling-Based Response-Guided Hepatitis C Treatment During Pregnancy and Postpartum. Open forum infectious diseases ; 10 2
- Etzion, O; Hamid, S; Lurie, Y; Gane, EJ; Yardeni, D; Duehren, S; Bader, N; Nevo-Shor, A; Channa, SM; Cotler, SJ; Mawani, M; Parkash, O; Dahari, H; Ingrid, C; Glenn, J Treatment of chronic hepatitis d with peginterferon lambda - the phase 2 LIMT-1 clinical trial. Hepatology (Baltimore, Md.) ;
- Mhlanga, A; Zakh, R; Churkin, A; Reinharz, V; Glenn, JS; Etzion, O; Cotler, SJ; Yurdaydin, C; Barash, D; Dahari, H Modeling the Interplay between HDV and HBV in Chronic HDV/HBV Patients. Mathematics (Basel, Switzerland) ; 10 20
- Sausen, DG; Shechter, O; Bietsch, W; Shi, Z; Miller, SM; Gallo, ES; Dahari, H; Borenstein, R Hepatitis B and Hepatitis D Viruses: A Comprehensive Update with an Immunological Focus. International journal of molecular sciences ; 23 24
- Shechter, O; Sausen, DG; Gallo, ES; Dahari, H; Borenstein, R Epstein-Barr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments. International journal of molecular sciences ; 23 22
- Reinharz, V; Churkin, A; Dahari, H; Barash, D Advances in Parameter Estimation and Learning from Data for Mathematical Models of Hepatitis C Viral Kinetics. Mathematics (Basel, Switzerland) ; 10 12
- Goyal, A; Churkin, A; Barash, D; Cotler, SJ; Shlomai, A; Etzion, O; Dahari, H Modeling-Based Response-Guided DAA Therapy for Chronic Hepatitis C to Identify Individuals for Shortening Treatment Duration. Open forum infectious diseases ; 9 5
- Tatara, E; Gutfraind, A; Collier, NT; Echevarria, D; Cotler, SJ; Major, ME; Ozik, J; Dahari, H; Boodram, B Modeling hepatitis C micro-elimination among people who inject drugs with direct-acting antivirals in metropolitan Chicago. PLoS ONE ; 17 3
- Shekhtman, L; Cotler, SJ; Ploss, A; Dahari, H Mathematical modeling suggests that entry-inhibitor Bulevirtide may interfere with hepatitis D virus clearance from circulation. Journal of Hepatology ;
- Boodram, B; Mackesy-Amiti, ME; Khanna, A; Brickman, B; Dahari, H; Ozik, J People who inject drugs in metropolitan Chicago: A meta-analysis of data from 1997-2017 to inform interventions and computational modeling toward hepatitis C microelimination. PLoS ONE ; 17 1
- Zakh, R; Churkin, A; Bietsch, W; Lachiany, M; Cotler, SJ; Ploss, A; Dahari, H; Barash, D A Mathematical Model for early HBV and -HDV Kinetics during Anti-HDV Treatment. Mathematics (Basel, Switzerland) ; 9 24
- Churkin, A; Kriss, S; Uziel, A; Goyal, A; Zakh, R; Cotler, SJ; Etzion, O; Shlomai, A; Rotstein, HG; Dahari, H; Barash, D Machine learning for mathematical models of HCV kinetics during antiviral therapy. Mathematical biosciences ;
- Bhutta, MS; Sausen, DG; Gallo, ES; Dahari, H; Doncel, GF; Borenstein, R Ginkgolic Acid Inhibits Coronavirus Strain 229E Infection of Human Epithelial Lung Cells. Pharmaceuticals (Basel, Switzerland) ; 14 10
- Shekhtman, L; Navasa, M; Sansone, N; Crespo, G; Subramanya, G; Chung, TL; Cardozo-Ojeda, EF; Pérez-Del-Pulgar, S; Perelson, AS; Cotler, SJ; Forns, X; Uprichard, SL; Dahari, H Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance. eLife ; 10
- Zakh, R; Churkin, A; Totzeck, F; Parr, M; Tuller, T; Etzion, O; Dahari, H; Roggendorf, M; Frishman, D; Barash, D A Mathematical Analysis of HDV Genotypes: From Molecules to Cells. Mathematics (Basel, Switzerland) ; 9 17
- Sausen, DG; Bhutta, MS; Gallo, ES; Dahari, H; Borenstein, R Stress-Induced Epstein-Barr Virus Reactivation. Biomolecules ; 11 9
- Durso-Cain, K; Kumberger, P; Schälte, Y; Fink, T; Dahari, H; Hasenauer, J; Uprichard, SL; Graw, F HCV Spread Kinetics Reveal Varying Contributions of Transmission Modes to Infection Dynamics. Viruses ; 13 7
- Reinharz, V; Ishida, Y; Tsuge, M; Durso-Cain, K; Chung, TL; Tateno, C; Perelson, AS; Uprichard, SL; Chayama, K; Dahari, H Understanding hepatitis B virus dynamics and the antiviral effect of interferon-a treatment in humanized chimeric mice. Journal of virology ;
- Dahari, H; Shlomai, A; Cotler, SJ Early HBV RNA kinetics under NA treatment may reveal new insights into HBV RNA dynamics and NA mode of action-more detailed kinetic studies are needed. Journal of viral hepatitis ;
- Kadelka, S; Dahari, H; Ciupe, SM Understanding the antiviral effects of RNAi-based therapy in HBeAg-positive chronic hepatitis B infection. Scientific reports ; 11 1
- Dasgupta, Swikriti; Imamura, Michio; Gorstein, Evan; Nakahara, Takashi; Tsuge, Masataka; Churkin, Alexander; Yardeni, David; Etzion, Ohad; Uprichard, Susan L; Barash, Danny; Cotler, Scott J; Dahari, Harel; Chayama, Kazuaki Modeling-Based Response-Guided Glecaprevir-Pibrentasvir Therapy for Chronic Hepatitis C to Identify Patients for Ultrashort Treatment Duration. Journal of Infectious Diseases ; 222 7
- Etzion, O; Dahari, H; Yardeni, D; Issachar, A; Nevo-Shor, A; Cohen-Naftaly, M; Ashur, Y; Uprichard, SL; Arbib, OS; Munteanu, D; Braun, M; Cotler, SJ; Abufreha, N; Keren-Naus, A; Shemer-Avni, Y; Mor, O; Murad, J; Novack, V; Shlomai, A Response guided therapy for reducing duration of direct acting antivirals in chronic hepatitis C infected patients: a Pilot study. Scientific reports ; 10 1
- Churkin, A; Reinharz, V; Lewkiewicz, S; Dahari, H; Barash, D HCVMultiscaleFit: A Simulator For Parameter Estimation in Multiscale Models Of Hepatitis C Virus Dynamics. AIP conference proceedings ; 2293
- Dahari, H; Vaillant, A; Cotler, SJ Letter to the Editor: Examining HBV RNA kinetics during NA treatment - are NA multifunctional antiviral agents? Hepatology (Baltimore, Md.) ;
- Churkin, A; Lewkiewicz, S; Reinharz, V; Dahari, H; Barash, D Efficient Methods for Parameter Estimation of Ordinary and Partial Differential Equation Models of Viral Hepatitis Kinetics. Mathematics (Basel, Switzerland) ; 8 9
- Chertow, DS; Shekhtman, L; Lurie, Y; Davey, RT; Heller, T; Dahari, H Modeling Challenges of Ebola Virus-Host Dynamics during Infection and Treatment. Viruses ; 12 1
- Dasgupta, S; Imamura, M; Gorstein, E; Nakahara, T; Tsuge, M; Churkin, A; Yardeni, D; Etzion, O; Uprichard, SL; Barash, D; Cotler, SJ; Dahari, H; Chayama, K Modeling-based response-guided therapy for chronic hepatitis C under glecaprevir/pibrentasvir may identify patients for ultra-short treatment duration. The Journal of infectious diseases ;
- Feld, JJ; Cypel, M; Kumar, D; Dahari, H; Pinto Ribeiro, RV; Marks, N; Kamkar, N; Bahinskaya, I; Onofrio, FQ; Zahoor, MA; Cerrochi, O; Tinckam, K; Kim, SJ; Schiff, J; Reichman, TW; McDonald, M; Alba, C; Waddell, TK; Sapisochin, G; Selzner, M; Keshavjee, S; Janssen, HLA; Hansen, BE; Singer, LG; Humar, A Short-course, direct-acting antivirals and ezetimibe to prevent HCV infection in recipients of organs from HCV-infected donors: a phase 3, single-centre, open-label study. The lancet. Gastroenterology & hepatology ; 5 7
- Shekhtman, L; Cotler, SJ; Hershkovich, L; Uprichard, SL; Bazinet, M; Pantea, V; Cebotarescu, V; Cojuhari, L; Jimbei, P; Krawczyk, A; Dittmer, U; Vaillant, A; Dahari, H Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg. Scientific reports ; 10 1
- Yardeni, D; Dizengof, V; Nevo-Shor, A; Abufreha, N; Dahari, H; Etzion, O Sustained virological response following an 11-day course of direct acting antiviral therapy for hepatitis C infection. Journal of gastrointestinal and liver diseases : JGLD ; 29 2
- Gorstein, E; Martinello, M; Churkin, A; Dasgupta, S; Walsh, K; Applegate, TL; Yardeni, D; Etzion, O; Uprichard, SL; Barash, D; Cotler, SJ; Matthews, GV; Dahari, H Modeling based response guided therapy in subjects with recent hepatitis C infection. Antiviral Research ; 180
- Tatara, E; Collier, NT; Ozik, J; Gutfraind, A; Cotler, SJ; Dahari, H; Major, M; Boodram, B MULTI-OBJECTIVE MODEL EXPLORATION OF HEPATITIS C ELIMINATION IN AN AGENT-BASED MODEL OF PEOPLE WHO INJECT DRUGS. Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference ; 2019
- Shteyer, E; Shekhtman, L; Zinger, T; Harari, S; Gafanovich, I; Wolf, D; Ivgi, H; Barsuk, R; Dery, I; Armoni, D; Rivkin, M; Pipalia, R; Cohen Eliav, M; Skorochod, Y; Breuer, GS; Tur-Kaspa, R; Weil Wiener, Y; Stern, A; Cotler, SJ; Dahari, H; Lurie, Y Modeling suggests that microliter volumes of contaminated blood caused an outbreak of hepatitis C during computerized tomography. PLoS ONE ; 14 1
- Koh, C; Dubey, P; Han, MAT; Walter, PJ; Garraffo, HM; Surana, P; Southall, NT; Borochov, N; Uprichard, SL; Cotler, SJ; Etzion, O; Heller, T; Dahari, H; Liang, TJ A randomized, proof-of-concept clinical trial on repurposing chlorcyclizine for the treatment of chronic hepatitis C. Antiviral Research ; 163
- Tsuge, M; Uchida, T; Walsh, K; Ishida, Y; Tateno, C; Kumar, U; Glenn, JS; Koh, C; Heller, T; Uprichard, SL; Dahari, H; Chayama, K Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection. Viruses ; 11 3
- Echevarria, D; Gutfraind, A; Boodram, B; Layden, J; Ozik, J; Page, K; Cotler, SJ; Major, M; Dahari, H Modeling indicates efficient vaccine-based interventions for the elimination of hepatitis C virus among persons who inject drugs in metropolitan Chicago. Vaccine ; 37 19
- Lhomme, S; DebRoy, S; Kamar, N; Abravanel, F; Metsu, D; Marion, O; Dimeglio, C; Cotler, SJ; Izopet, J; Dahari, H Plasma Hepatitis E Virus Kinetics in Solid Organ Transplant Patients Receiving Ribavirin. Viruses ; 11 7
- Reinharz, V; Churkin, A; Lewkiewicz, S; Dahari, H; Barash, D A Parameter Estimation Method for Multiscale Models of Hepatitis C Virus Dynamics. Bulletin of mathematical biology ; 81 10
- Ishida, Y; Chung, TL; Imamura, M; Hiraga, N; Sen, S; Yokomichi, H; Tateno, C; Canini, L; Perelson, AS; Uprichard, SL; Dahari, H; Chayama, K Acute hepatitis B virus infection in humanized chimeric mice has multiphasic viral kinetics. Hepatology (Baltimore, Md.) ; 68 2
- Boodram, Basmattee; Hotton, Anna L.; Shekhtman, Louis; Gutfraind, Alexander; Dahari, Harel High-Risk Geographic Mobility Patterns among Young Urban and Suburban Persons who Inject Drugs and their Injection Network Members. Journal of Urban Health ; 95 1
- Gambato, M; Canini, L; Lens, S; Graw, F; Perpiñan, E; Londoño, MC; Uprichard, SL; Mariño, Z; Reverter, E; Bartres, C; González, P; Pla, A; Costa, J; Burra, P; Cotler, SJ; Forns, X; Dahari, H Early HCV viral kinetics under DAAs may optimize duration of therapy in patients with compensated cirrhosis. Liver international : official journal of the International Association for the Study of the Liver ; 39 5
- Kumberger, P; Durso-Cain, K; Uprichard, SL; Dahari, H; Graw, F Accounting for Space—Quantification of Cell-To-Cell Transmission Kinetics Using Virus Dynamics Models. Viruses ; 10 4
- Major, M; Gutfraind, A; Shekhtman, L; Cui, Q; Kachko, A; Cotler, SJ; Hajarizadeh, B; Sacks-Davis, R; Page, K; Boodram, B; Dahari, H Modeling of patient virus titers suggests that availability of a vaccine could reduce hepatitis C virus transmission among injecting drug users. Science translational medicine ; 10 449
- Reinharz, V; Churkin, A; Dahari, H; Barash, D A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics. Frontiers in applied mathematics and statistics ; 3
- Canini, L; DebRoy, S; Mariño, Z; Conway, JM; Crespo, G; Navasa, M; D'Amato, M; Ferenci, P; Cotler, SJ; Forns, X; Perelson, AS; Dahari, H Severity of liver disease affects HCV kinetics in patients treated with intravenous silibinin monotherapy. ANTIVIRAL THERAPY ; 20 2
- Guedj, J; Canini, L; Cotler, S; Dahari, H Reply: To PMID 25098971. Hepatology (Baltimore, Md.) ; 61 6
- Rong, L; Guedj, J; Dahari, H; Perelson, AS Treatment of hepatitis C with an interferon-based lead-in phase: a perspective from mathematical modelling. ANTIVIRAL THERAPY ; 19 5