Profile Image
Karen Griffin Photo
Name
Karen Griffin
Degree
M.D.
FACP
Rank
Professor
Primary Department
Nephrology
Appointment Request
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Specialties
Chronic Kidney Disease
High Blood Pressure
Systemic Lupus Erythematosus
Polycystic Kidney Disease
Kidney Stones
Diabetic Kidney Disease
Hypertension
Peritoneal Dialysis
Nephrolithiasis
Electrolyte Abnormalities
Potassium
Sodium
Magnesium
Glomerulonephritis
Vasculitis
Nephritis
Locations
Loyola Hospital
Loyola Outpatient Center
Certifications
American Board of Internal Medicine
Nephrology, American Board of Internal Medicine Subspecialty
Education
Medical School
Rush Medical College of Rush University
Residencies
Rush-Presbyterian-St. Luke's Medical Center, Internal Medicine: General
Fellowships
Rush-Presbyterian-St. Luke's Medical Center, Internal Medicine: Nephrology
Hobbies
Bicycling
Exercise
Gardening
Fishing
Publications
Griffin,K. A.Hypertensive Kidney Injury and the Progression of Chronic Kidney Disease Hypertension (Dallas, Tex.: 1979) 2017 ;70(4):687-694
Small,C.; Kramer,H. J.; Griffin,K. A.; Vellanki,K.; Leehey,D. J.; Bansal,V. K.; Markossian,T. W.Non-dialysis dependent chronic kidney disease is associated with high total and out-of-pocket healthcare expenditures BMC Nephrology 2017 ;18(1):3-016-0432-2
Polichnowski,A. J.; Griffin,K. A.; Picken,M. M.; Licea-Vargas,H.; Long,J.; Williamson,G. A.; Bidani,A. K.Hemodynamic basis for the limited renal injury in rats with angiotensin II-induced hypertension American journal of physiology.Renal physiology 2015 ;308(3):F252-60
Polichnowski,A. J.; Licea-Vargas,H.; Picken,M. M.; Long,J.; Bisla,R.; Williamson,G. A.; Bidani,A. K.; Griffin,K. A.Glomerulosclerosis in the diet-induced obesity model correlates with sensitivity to nitric oxide inhibition but not glomerular hyperfiltration or hypertrophy American journal of physiology.Renal physiology 2015 ; :ajprenal.00211.2015
Polichnowski,A. J.; Lan,R.; Geng,H.; Griffin,K. A.; Venkatachalam,M. A.; Bidani,A. K.Severe renal mass reduction impairs recovery and promotes fibrosis after AKI Journal of the American Society of Nephrology : JASN 2014 ;25(7):1496-1507
Griffin,K. A.; Polichnowski,A.; Litbarg,N.; Picken,M.; Venkatachalam,M. A.; Bidani,A. K.Critical blood pressure threshold dependence of hypertensive injury and repair in a malignant nephrosclerosis model Hypertension 2014 ;64(4):801-807
Bidani,A. K.; Polichnowski,A. J.; Loutzenhiser,R.; Griffin,K. A.Renal microvascular dysfunction, hypertension and CKD progression CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 2013 ;22(1):1-9
Polichnowski,A. J.; Griffin,K. A.; Long,J.; Williamson,G. A.; Bidani,A. K.Blood pressure-renal blood flow relationships in conscious angiotensin II- and phenylephrine-infused rats American journal of physiology.Renal physiology 2013 ;305(7):F1074-84
Griffin,K.; Polichnowski,A.; Licea-Vargas,H.; Picken,M.; Long,J.; Williamson,G.; Bidani,A.Large BP-dependent and -independent differences in susceptibility to nephropathy after nitric oxide inhibition in Sprague-Dawley rats from two major suppliers. American Journal of Physiology - Renal Physiology 2012 ;302(1):F173-82
Griffin,K. A.; Polichnowski,A. J.; Licea-Vargas,H.; Picken,M.; Long,J.; Williamson,G. A.; Bidani,A. K.Large Bp-Dependent and -Independent Differences in Susceptibility to Nephropathy After Nitric Oxide Inhibition in Sprague-Dawley Rats from Two Major Suppliers American journal of physiology.Renal physiology 2011 ; :
Herek,J. I.; FitzGerald,M. P.; Mohindra,M.; Wickman,C.; Leehey,D. J.; Bidani,A. K.; Griffin,K. A.Solute and water excretion patterns in patients with nocturnal polyuria International Journal of Nephrology & Urology 2010 ;2(4):526-531
Bidani,A. K.; Griffin,K. A.; Williamson,G.; Wang,X.; Loutzenhiser,R.Protective importance of the myogenic response in the renal circulation Hypertension 2009 ;54(2):393-398
Griffin,K. A.; Bidani,A. K.Angiotensin II type 2 receptor in chronic kidney disease: the good side of angiotensin II?. Kidney international 2009 ;75(10):1006-1008
Griffin,K. A.; Bidani,A. K.Potential Risks of Calcium Channel Blockers in Chronic Kidney Disease. Current Cardiology Reports 2008 ;10:448-455
Griffin,K. A.; Kramer,H.; Bidani,A. K.Adverse renal consequences of obesity American Journal of Physiology - Renal Physiology 2008 ;294(4):F685-96
Pravenec,M.; Churchill,P. C.; Churchill,M. C.; Viklicky,O.; Kazdova,L.; Aitman,T. J.; Petretto,E.; Hubner,N.; Wallace,C. A.; Zimdahl,H.; Zidek,V.; Landa,V.; Dunbar,J.; Bidani,A. K.; Griffin,K.; Qi,N.; Maxova,M.; Kren,V.; Mlejnek,P.; Wang,J.; Kurtz,T. W.Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nature genetics 2008 ;40(8):952-954
Williamson,G. A.; Loutzenhiser,R.; Wang,X.; Griffin,K. A.; Bidani,A. K.Systolic and mean blood pressures and afferent arteriolar myogenic response dynamics: a modeling approach. American Journal of Physiology.Regulatory, Integrative and Comparative Physiology 2008 ;295(5):R1502-R1511
Bidani,A. K.; Picken,M. M.; Hacioglu,R.; Williamson,G.; Griffin,K. A.Spontaneously reduced blood pressure load in the rat streptozotocin-induced diabetes model: potential pathogenetic relevance. American Journal of Physiology - Renal Physiology 2007 ;292(2):F647-54
Griffin,K. A.; Abu-Naser,M.; Abu-Amarah,I.; Picken,M. M.; Williamson,G. A.; Bidani,A. K.Dynamic blood pressure load and nephropathy in the ZSF1 (fa/fa cp) model of type 2 diabetes. American Journal of Physiology - Renal Physiology 2007 ;293(5):F1605-13
Hacioglu,R.; Williamson,G. A.; Abu-Amarah,I.; Griffin,K. A.; Bidani,A. K.Characterization of dynamics in renal autoregulation using volterra models. IEEE Transactions on Biomedical Engineering 2006 ;53(11):2166-2176
Bidani,A. K.; Griffin,K. A.The benefits of renin-angiotensin blockade in hypertension are dependent on blood-pressure lowering. Nature Clinical Practice Nephrology 2006 ;2(10):542-543
Loutzenhiser,R.; Griffin,K.; Williamson,G.; Bidani,A. K.Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanisms American Journal of Physiology - Regulatory Integrative & Comparative Physiology 2006 ;290(5):R1153-67
Loutzenhiser,R.; Griffin,K. A.; Bidani,A. K.Systolic blood pressure as the trigger for the renal myogenic response: protective or autoregulatory? Current Opinion in Nephrology & Hypertension 2006 ;15(1):41-49
Griffin,K. A.Hypertension and kidney damage. Journal of clinical hypertension 2006 ;8(3):209-214
Griffin,K. A.; Bidani,A. K.Progression of renal disease: renoprotective specificity of renin-angiotensin system blockade Clinical Journal of The American Society of Nephrology: CJASN 2006 ;1(5):1054-1065
Kurtz,T. W.; Griffin,K. A.; Bidani,A. K.; Davisson,R. L.; Hall,J. E.Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the Council on High Blood Pressure Research, Professional and Public Education Subcommittee Arteriosclerosis, Thrombosis & Vascular Biology 2005 ;25(3):478-479
Kurtz,T. W.; Griffin,K. A.; Bidani,A. K.; Davisson,R. L.; Hall,J. E.Recommendations for blood pressure measurement in humans and experimental animals. Part 2: Blood pressure measurement in experimental animals: a statement for professionals from the subcommittee of professional and public education of the American Heart Association council on high blood pressure research Hypertension 2005 ;45(2):299-310
Abu-Amarah,I.; Bidani,A. K.; Hacioglu,R.; Williamson,G. A.; Griffin,K. A.Differential effects of salt on renal hemodynamics and potential pressure transmission in stroke-prone and stroke-resistant spontaneously hypertensive rats. American Journal of Physiology - Renal Physiology 2005 ;289(2):F305-13
Bidani,A. K.; Griffin,K. A.Pathophysiology of hypertensive renal damage: implications for therapy Hypertension 2004 ;44(5):595-601
Griffin,K. A.; Bidani,A. K.Hypertensive renal damage: insights from animal models and clinical relevance Current hypertension reports 2004 ;6(2):145-153
Griffin,K. A.; Hacioglu,R.; Abu-Amarah,I.; Loutzenhiser,R.; Williamson,G. A.; Bidani,A. K.Effects of calcium channel blockers on "dynamic" and "steady-state step" renal autoregulation. American Journal of Physiology - Renal Physiology 2004 ;286(6):F1136-43
Griffin,K. A.; Picken,M. M.; Bidani,A. K.Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat. Kidney international 2004 ;65(1):209-218
Griffin,K. A.; Abu-Amarah,I.; Bidani,A. K.Long-term blood-pressure monitoring in unrestrained animals. Methods in Molecular Medicine 2003 ;86:329-340
Griffin,K. A.; Abu-Amarah,I.; Picken,M. M.; Bidani,A. K.Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent Hypertension 2003 ;41(2):201-206
Bidani,A. K.; Hacioglu,R.; Abu-Amarah,I.; Williamson,G. A.; Loutzenhiser,R.; Griffin,K. A."Step" vs. "dynamic" autoregulation: implications for susceptibility to hypertensive injury. American Journal of Physiology - Renal Physiology 2003 ;285(1):F113-20
Griffin,K. A.; Picken,M. M.; Giobbie-Hurder,A.; Bidani,A. K.Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms. Kidney international 2003 ;63(2):607-616
Bidani,A. K.; Griffin,K. A.Long-term renal consequences of hypertension for normal and diseased kidneys Current Opinion in Nephrology & Hypertension 2002 ;11(1):73-80
Churchill,P. C.; Churchill,M. C.; Griffin,K. A.; Picken,M. M.; Webb,R. C.; Kurtz,T. W.; Bidani,A. K.Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat. Kidney international 2002 ;61(5):1794-1800
Griffin,K. A.; Churchill,P. C.; Picken,M. M.; Webb,R. C.; Kurtz,T. W.; Bidani,A. K.Differential salt-sensitivity in the pathogenesis of renal damage in SHR and stroke prone SHR. American Journal of Hypertension 2001 ;14(4 Pt 1):311-320
Griffin,K. A.; Picken,M. M.; Bakris,G.; Bidani,A. K.Relative antihypertensive and glomeruloprotective efficacies of enalapril and candesartan cilexetil in the remnant kidney model. Journal of Renin-Angiotensin-Aldosterone System 2001 ;2(1):s191-s195
Griffin,K. A.; Picken,M. M.; Bakris,G. L.; Bidani,A. K.Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model. Hypertension 2001 ;37(5):1268-1272
Bidani,A. K.; Griffin,K. A.; Churchill,P. C.; Churchill,M. C.; St Lezin,E.; Kurtz,T. W.Genetic susceptibility to renal injury in hypertension Experimental nephrology 2001 ;9(6):360-365
Bidani,A. K.; Griffin,K. A.; Bakris,G.; Picken,M. M.Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation Kidney international 2000 ;57(4):1651-1661
Griffin,K. A.; Picken,M. M.; Churchill,M.; Churchill,P.; Bidani,A. K.Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat. Journal of the American Society of Nephrology 2000 ;11(3):497-506