Dr. Doerte Lehman
PhD, Northwestern University, Evanston, IL, 2013
Dr. Xufang Deng
PhD, Shanghai Veterinary Research Institute, CAAS, China, 2011
Coronaviruses cause important human and animal disease with respiratory, gastrointestinal and neurological symptoms. The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged from Guangdong province of China in 2003, which infected more than 8000 people worldwide with 10 percent mortality, promotes to investigate the viral pathogenesis and to develop antiviral agents. In previous studies of Dr. Baker’ Lab, the Papain-like proteases (PLPs) of coronaviruses have been identified to possess deubiquitinating enzyme, deISGylating enzyme activities and act as IFN antagonism. My research mainly focuses on further elucidating the mechanism of PLpro-mediated evasion of innate immune response. Read More.
Dr. Tyler Boone
PhD, University of Alberta, Edmonton, Alberta, Canada, 2012
Bacillus anthracis remains a biological threat, both as a potential weapon and as a natural pathogen in areas where it is endemic. The overall goal to my research is to develop a novel vaccine targeting the B. anthracis spore, which could be used to prevent disease caused by B. anthracis. To date, I have produced and purified a number of spore surface proteins as well as one subunit of the toxin, which have been assayed in a mouse model for their ability to induce an immune response. Since it is possible to modify the outer surface of the B. anthracis spore, through mechanical and genetic methods, without affecting virulence it is necessary to identify antigens that would be surface expressed under these conditions. Read More.
Dr. Adarsh Dharan
Ph.D., Hannover Medical School, Germany, 2013
Dr. Sevnur Komurlu
Ph.D., University of Florida, 2012
Dr. Wei Ping Teoh