News

Congratulations to Nancy Zeleznik-Le, PhD

Congratulations to Nancy Zeleznik-Le, PhD, for her promotion to Chair of Stritch’s Department of Cancer Biology, effective September 1, 2019. Since joining Loyola University Chicago as an Assistant Professor in 1999, Zeleznik-Le has moved up the ranks, most recently as a Professor in the Department of Medicine and co-director of the Oncology Research Institute. In July 2018, Zeleznik-Le was named interim Chair of the new Department of Cancer Biology, which was created to be Stritch’s center for cancer-related research.   

As Chair, Zeleznik-Le will be responsible for establishing departmental goals, as well as promoting excellence in teaching, research, and service. She will continue in her role as Deputy Director and Associate Director for Basic Research at the Cardinal Bernardin Cancer Center. She will continue to lead the Cancer Gene Regulation Program with research focusing on the Mixed Lineage Leukemia (MLL) gene and MLL-fusion proteins that cause leukemia.   

Zeleznik-Le received her BS in Microbiology and Immunology from the Ohio State University and her PhD in Immunology and Cellular and Molecular Biology from Duke University.  She completed her postdoctoral fellowship in Molecular Biology at the University of North Carolina at Chapel Hill’s Lineberger Cancer Research Center.  

 

Summer Student Research Internship Symposium

On July 30, 2018 seven LUC undergraduate science majors presented at the third annual Summer Research Internship Symposium.   The symposium was the culmination of the ten-week research internship at Loyola’s Cardinal Bernardin Cancer Center. 

Mike Nishimura ‌‌Father Breslin Co/Program leader

 

The Cancer Signaling Symposium was held on Friday, April 27th in our Center for Translational Research & Education.
The all day symposium featured seven prominent scientists in the field of cancer research.  

 
                                                                        Symposium speakers and Loyola University Faculty

Awards

The NIH's National Cancer Institute has funded Dr. Jiwang Zhang's proposal, "RIP1/RIP3-Calpain-Stat3 and NF-kappa B pathways in AML pathogenesis and treatment"

The American Society of Hematology awarded Dr. Nancy Zeleznik-Le's proposal, "Structure/Function of AF9 in Hematopoiesis and Leukemia"

The Research Funding Committee has awarded Dr. Maurizio Bocchetta's for his proposal, "Specific, CROSPR-mediated ablation of the deubiquitinase OTUD6B isoforms in non-small cell lung cancer (NSCLC) cells".
(RFC 07/01/2018-06/30/2019)

 

Publications

Andrew Baker, PhD graduate of the Clodia Osipo lab has published: "Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival" Baker A, Wyatt D, Bocchetta M, Li J, Filipovic A, Green A, Peiffer DS, Fuqua S, Miele L, Albain KS, Osipo C. Oncogene. 2018 May 10. doi: 10.1038/s41388-018-0251-y. [Epub ahead of print]

Deep Shah, PhD graduate of the Clodia Osipo lab has published: "Inhibition of HER2 Enriches for Jagged1-dependent Breast Cancer Stem Cells: Role for Membrane Jagged1"  Deep Shah, Debra Wyatt, Andrew Baker, Patricia Simms, Daniel Peiffer, Michelle Fernandez, Emad Rakha, Andrew Green, Aleksandra Filipovic, Lucio Miele, and Clodia Osipo.
Clinical Cancer Research. 2018. Accepted for publication

Stephanie Watkins, PhD and PhD candidate Flor Navarro,  "Estrogen Stimulation Differentially Impacts Human Male and Female Antigen-Specific T Cell Anti-Tumor Function and Polyfunctionality"  published in Volume 1, Issue 4 of Gender and the Genome.  It has been selected by the Foundation for Gender Specific Medicine for the Robert S. Birch award as the best research study in Gender specific medicine.  It is now featured on their website   https://gendermed.org/the-foundation-for-gender-specific-medicine-announces-the-winners-of-the-robert-s-birch-award/ and on the cover of an upcoming issue of the journal.

The anticipated cover of the Journal of Leukocyte Biology will feature a figure from the recent article of graduate students Tim Spear and Kendra Foley of the Nishimura lab. "TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence". PMID: 29350789