News

New Publications:

Stephanie Berg, MD
Evens AM, Danilov AV, Jagadeesh D, Sperling AL, Kim SH, Vaca RA, Wei C, Rector D, …, Berg S, …, Alderuccio JP. Burkitt Lymphoma in the Modern Era: Real World Outcomes and Prognostication Across 30 US Cancer Centers. Blood. 2020 Jul 14:blood.2020006926. doi: 10.1182/blood.2020006926. Epub ahead of print. PMID: 32663292.
https://pubmed.ncbi.nlm.nih.gov/32663292/

Weihang (Valerie) Chai, PhD
Lyu X, Lei KH, Biak Sang P, Shiva O, Chastain M, Chi P, Chai W. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. EMBO J. 2021 Jan 15;40(2):e103654. doi: 10.15252/embj.2019103654. Epub 2020 Nov 19. PMID: 33210317; PMCID: PMC7809791.
https://pubmed.ncbi.nlm.nih.gov/33210317/

Nguyen DD, Kim EY, Sang PB, Chai W. Roles of OB-Fold Proteins in Replication Stress. Front Cell Dev Biol. 2020 Sep 11;8:574466. doi: 10.3389/fcell.2020.574466. PMID: 33043007; PMCID: PMC7517361.
https://pubmed.ncbi.nlm.nih.gov/33043007/ 

Mitchell Denning, PhD
Wang F, Hou W, Chitsike L, Xu Y, Bettler C, Perera A, Bank T, Cotler SJ, …, Denning MF, …, Qiu W. ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice. Gastroenterology. 2020 Jul;159(1):289-305.e16. doi: 10.1053/j.gastro.2020.03.013. Epub 2020 Jun 24. PMID: 32171747; PMCID: PMC7387191.
https://pubmed.ncbi.nlm.nih.gov/32171747/

Andrew Dingwall, PhD
Ford DJ, Zraly CB, Perez JH, Dingwall AK. The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate. Dev Biol. 2020 Dec 1;468(1-2):41-53. doi: 10.1016/j.ydbio.2020.09.007. Epub 2020 Sep 16. PMID: 32946789.
https://pubmed.ncbi.nlm.nih.gov/32946789/ 

Zraly CB, Zakkar A, Perez JH, Ng J, White KP, Slattery M, Dingwall AK. The Drosophila MLR COMPASS complex is essential for programming cis-regulatory information and maintaining epigenetic memory during development. Nucleic Acids Res. 2020 Apr 17;48(7):3476-3495. doi: 10.1093/nar/gkaa082. PMID: 32052053; PMCID: PMC7144903..https://pubmed.ncbi.nlm.nih.gov/32052053/ 

Sean Fanning, PhD
Abderrahman B, Maximov PY, Curpan RF, Fanning SW, Hanspal JS, Fan P, Foulds CE, Chen Y, Malovannaya A, …, Jordan VC. Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 Jan;20(1):11-25. doi: 10.1158/1535-7163.MCT-20-0563. Epub 2020 Nov 11. PMID: 33177154; PMCID: PMC7790886.
https://pubmed.ncbi.nlm.nih.gov/33177154/ 

Maximov PY, Abderrahman B, Hawsawi YM, Chen Y, Foulds CE, Jain A, Malovannaya A, Fan P, …, Fanning SW, …, Jordan VC. The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells. Mol Pharmacol. 2020 Jul;98(1):24-37. doi: 10.1124/mol.120.119776. Epub 2020 May 3. PMID: 32362585; PMCID: PMC7294906.
https://pubmed.ncbi.nlm.nih.gov/32362585/ 

Jose Guevara-Patino, MD, PhD
Burke B, Eden C, Perez C, Belshoff A, Hart S, Plaza-Rojas L, Delos Reyes M, Prajapati K, Voelkel-Johnson C, …, Guevara-Patiño J. Inhibition of Histone Deacetylase (HDAC) Enhances Checkpoint Blockade Efficacy by Rendering Bladder Cancer Cells Visible for T Cell-Mediated Destruction. Front Oncol. 2020 May 15;10:699. doi: 10.3389/fonc.2020.00699. PMID: 32500025; PMCID: PMC7243798.
https://pubmed.ncbi.nlm.nih.gov/32500025/ 

Guevara-Patiño JA, Plaza-Rojas L. It Takes Two to Tango. J Invest Dermatol. 2020 Jun;140(6):1131-1133. doi: 10.1016/j.jid.2020.01.017. PMID: 32446332.
https://pubmed.ncbi.nlm.nih.gov/32446332/ 

Charles Hemenway, MD, PhD
Mehrhoff CJ, Hemenway CS, Suh E. Emergence of a Ph-negative Clone in a Child With Ph+ ALL. J Pediatr Hematol Oncol. 2020 Aug;42(6):e466-e468. doi: 10.1097/MPH.0000000000001521. PMID: 31149920.
https://pubmed.ncbi.nlm.nih.gov/31149920/ 

Irida Kastrati, PhD
1: Kastrati I, Joosten SEP, Semina SE, Alejo LH, Brovkovych SD, Stender JD, Horlings HM, Kok M, Alarid ET, …, Frasor J. The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers. Mol Cancer Res. 2020 Jul;18(7):1018-1027. doi: 10.1158/1541-7786.MCR-19-1082. Epub 2020 Apr 3. PMID: 32245803; PMCID: PMC7335344.
https://pubmed.ncbi.nlm.nih.gov/32245803/ 

Michael Nishimura, PhD
Nelson MH, Knochelmann HM, Bailey SR, Huff LW, Bowers JS, Majchrzak-Kuligowska K, Wyatt MM, Rubinstein MP, …, Nishimura MI, …, Paulos CM. Identification of human CD4+ T cell populations with distinct antitumor activity. Sci Adv. 2020 Jul 1;6(27):eaba7443. doi: 10.1126/sciadv.aba7443. PMID: 32937437; PMCID: PMC7458458.
https://pubmed.ncbi.nlm.nih.gov/32937437/ 

Pulido I, Ollosi S, Aparisi S, Becker JH, Aliena-Valero A, Benet M, Rodríguez ML, López A, …, Nishimura MI, …, Shimamura T. Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma. Cancer Res. 2020 Oct 1;80(19):4224-4232. doi: 10.1158/0008-5472.CAN-20-0141. Epub 2020 Aug 3. PMID: 32747363; PMCID: PMC7541638.
https://pubmed.ncbi.nlm.nih.gov/32747363/ 

Moore TV, Nishimura MI. Improved MHC II epitope prediction - a step towards personalized medicine. Nat Rev Clin Oncol. 2020 Feb;17(2):71-72. doi: 10.1038/s41571-019-0315-0. PMID: 31836878; PMCID: PMC7223749.
https://pubmed.ncbi.nlm.nih.gov/31836878/ 

Clodia Osipo, PhD
BeLow M, Osipo C. Notch Signaling in Breast Cancer: A Role in Drug Resistance. Cells. 2020 Sep 29;9(10):2204. doi: 10.3390/cells9102204. PMID: 33003540; PMCID: PMC7601482.
https://pubmed.ncbi.nlm.nih.gov/33003540/ 

Peiffer DS, Ma E, Wyatt D, Albain KS, Osipo C. DAXX-inducing phytoestrogens inhibit ER+ tumor initiating cells and delay tumor development. NPJ Breast Cancer. 2020 Aug 14;6:37. doi: 10.1038/s41523-020-00178-5. PMID: 32864429; PMCID: PMC7429502.
https://pubmed.ncbi.nlm.nih.gov/32864429/ 

Wei Qiu, PhD
Pulido I, Ollosi S, Aparisi S, Becker JH, Aliena-Valero A, Benet M, Rodríguez ML, López A, …, Qiu W, …, Shimamura T. Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non- Small Cell Lung Carcinoma. Cancer Res. 2020 Oct 1;80(19):4224-4232. doi: 10.1158/0008-5472.CAN-20-0141. Epub 2020 Aug 3. PMID: 32747363; PMCID: PMC7541638.
https://pubmed.ncbi.nlm.nih.gov/32747363/

Wang F, Hou W, Chitsike L, Xu Y, Bettler C, Perera A, Bank T, Cotler SJ, Dhanarajan A, …, Qiu W. ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice. Gastroenterology. 2020 Jul;159(1):289-305.e16. doi: 10.1053/j.gastro.2020.03.013. Epub 2020 Jun 24. PMID: 32171747; PMCID: PMC7387191.
https://pubmed.ncbi.nlm.nih.gov/32171747/

Nancy Zeleznik-Le, PhD
Schmidt CR, Achille NJ, Kuntimaddi A, Boulton AM, Leach BI, Zhang S, Zeleznik-Le NJ, Bushweller JH. BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. Blood Cancer Discov. 2020 Sep;1(2):162-177. doi: 10.1158/2643-3230.BCD-20-0036. PMID: 32954361; PMCID: PMC7497807.. 
https://pubmed.ncbi.nlm.nih.gov/32954361/ 

Jiwang Zhang, PhD
Zhang L, Mack R, Breslin P, Zhang J. Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches. J Hematol Oncol. 2020 Nov 23;13(1):157. doi: 10.1186/s13045-020-00994-z. PMID: 33228751; PMCID: PMC7686726.
https://pubmed.ncbi.nlm.nih.gov/33228751/ 

Sheng Y, Ma R, Yu C, Wu Q, Zhang S, Paulsen K, Zhang J, Ni H, Huang Y, …, Qian Z. Role of c-Myc haploinsufficiency in the maintenance of HSCs. Blood. 2020 Aug 21:blood.2019004688. doi: 10.1182/blood.2019004688. Epub ahead of print. PMID: 32822452.https://pubmed.ncbi.nlm.nih.gov/32822452/ 

Zhang L, Li J, Xu H, Shao X, Fu L, Hou Y, Hao C, Li W, …, Zhang J, Zhang J. Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ. Blood. 2020 Apr 2;135(14):1133-1145. doi: 10.1182/blood.2019001863. PMID: 32040550.
https://pubmed.ncbi.nlm.nih.gov/32040550/

2020

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