Irida Kastrati, PhD



Assistant Professor, Cancer Biology

CBCC 233

Laboratory Website: 

Research Focus Areas

  • Breast cancer
  • Racial disparity in breast cancer
  • Therapy resistance and recurrence
  • New therapeutic targets and drug discovery

Worldwide, breast cancer accounts for nearly a quarter of all cancers in women and it is estimated that 1.7 million women are diagnosed with the disease annually. Most breast cancer deaths are due to aggressive therapy-resistant disease that eventually spreads to other parts of the body (metastasis). Our longstanding interest is to apply a multi-disciplinary approach to identify the fundamental cancer biology of deadly disease. Then, we implement drug discovery tools and evaluate novel therapeutics to improve patient outcome and reduce mortality. More recently, our lab is also working to address the racial disparity in breast cancer. Despite similar incidence, African American women die of breast cancer at a much higher rate than Caucasian women. In the Chicago area, this disparity is even more pronounced than the nation as a whole. While the reasons behind this disparity are multifactorial, recent data also point to biological components. Our goal is to identify these biological drivers and develop therapeutic strategies to eliminate disparity. 

Departmental Program: Cancer Cell Biology and Signaling

Education / Training:

PhD:   University of Illinois at Chicago, Chicago, IL  USA

Irida Kastrati Publications