Clinical Trials

Loyola University Medical Center Radiation Oncology is currently participating in the following clinical trials:



RTOG 1071/NCCTGN0577 – Phase III Intergroup Study of Radiotherapy versus Temozolomide Alone versus Radiotherapy Concomitant with Adjuvant Temozolomide for Patients with 1p/19q Codeleted Anaplastic Glioma.

  • Clinical Identifier: NCT00869401


TARGIT US - Targeted Intraoperative Radiotherapy After Conservation Breast Surgery For Women With Early Stage Breast Cancer: A Phase IV Registry Trial.

  • Clinical Identifier: NCT01570998


RTOG 1304/NSABP B51 - A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post- Lumpectomy Regional Nodal XRT in patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy.

  • Clinical Identifier: NCT01872975


RTOG 0920 - A Phase III Study Of Postoperative Radiation Therapy (IMRT) +/- Cetuximab For Locally-Advanced Resected Head And Neck Cancer

  • Clinical Identifier: NCT 00956007


IIT - SBRT for Early NSCLC - Phase II Study of Stereotactic Body Radiation Therapy for Unbiopsied Early-stage Non-small Cell Lung Cancer.

  • Clinical Identifier: Pending


RTOG 1306 – A Randomized Phase II Study of Individualized Combined Modality Therapy for Stage III Non-Small Cell Lung Cancer(NSCLC).

  • Clinical Identifier: NCT01822496


RTOG 0848 - A Phase II-R and A Phase III Trial Evaluating both *Erlotinib (PH IIR) and Chemoradiation (PH III) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma.”

  • Clinical Identifier: NCT01013649


PanCRS – Pancreatic Cancer Radiotherapy Study Group (PanCRS) Trial: A Randomized Phase III Study Evaluating Modified FOLFIRINOX (mFFX) with or without Stereotactic Body Radiotherapy (SBRT) in the Treatment of Locally Advanced Pancreatic Cancer.

  • Clinical Identifier: NCT01926197


IIT - IORT Pancreas- Phase I Study of Low Kilovoltage Intraoperative Radiation for Patients with Resectable Pancreatic Adenocarcinoma.

  • Clinical Identifier: NCT02599662


TACE - A Pilot Randomized Trial of Transarterial Chemoembolization With or Without Stereotactic Body Radiation Therapy For Hepatocellular Carcinoma Patients Awaiting Liver Transplantation. 

  • Clinical Identifier: NCT02150317


NRG GU001 - Randomized Phase II Trial of Postoperative Adjuvant IMRT Following Cystectomy For pT3/pT4 Urothelial Bladder Cancer.

  • Clinical Identifier: NCT12316548


IIT - HDR Brachytherapy Prostate - A prospective database of high-dose-rate prostate brachytherapy.
ate-risk prostate cancer.

  • Clinical Identifier: Pending


RTOG 1174 - A Phase III Trial Of Adjuvant Chemotherapy As Primary Treatment For Locally Advanced Cervical Cancer Compared To Chemoradiation Alone: The Outback Trial.  

  • Clinical Identifier:  NCT01414608


IIT - MRI Based Brachytherapy for Cancer of the Cervix - A Prospective Trial of MRI-Based Brachytherapy for the Treatment of Carcinoma of the Cervix.

  • Clinical Identifier: Pending


GOG 0238 - A Randomized Trial of Pelvic Irradiation With or Without Concurrent Weekly Cisplatin in Patients With Pelvic-Only Recurrence of Carcinoma of the Uterine Corpus. 

  • Clinical Identifier: NCT00492778


KYPHO IORT - Combining Intraoperative Radiotherapy with Kyphoplasty for Treatment of Spinal Metastases.

  • Clinical Identifier: NCT02480036


RTOG 0631 – Phase II/III Study of Image-Guided Radiosurgery/SBRT for Localized Spine Metastasis.

  • Clinical Identifier: NCT00922974


NRG BR001 - A Phase I Study of Stereotactic Body Radiotherapy (SBRT) for the Treatment of Multiple Metastases

  • Clinical Identifier: NCT02206334


NRG BR002 - A Phase IIR/III Trial of Standard of Care Therapy with or without Stereotactic Body Radiotherapy (SBRT) and/ or Surgical Ablation for Newly Oligometastatic Breast Cancer. 

  • Clinical Identifier: NCT02364557

For more information about Radiation Oncology Clinical Trials at Loyola,

please contact

Beth Chiappetta, RN at or call 708-216-2568.