CORNEA PUBLICATIONS

Cornea Publications (2017-Present)

2023

  1. Brahmbhatt P, Khanna S, Griffin S, Bouchard CS. A Retrospective Analysis of Tear Film and Blink Parameters in Patients With Ocular Surface Disease. Eye Contact Lens. 2023 May 11. doi: 10.1097/ICL.0000000000000994. Epub ahead of print. PMID: 37167586.
  2. Ueta M, Inoue C, Nakata M, Sotozono C, Kim MK, Wakamatsu T, Jongkhajornpong P, Saeed H, Rauz S, Ma D, Yoon KC, Puansricharern V, Bouchard CS, Ahmad S, Seo KY, Joo CK, Gomes JA, Kinoshita JC, Teramukai S. Severe Ocular Complications of SJS/TEN and associations between pre-onset, acute and chronic factors: a report from the International Ophthalmology Collaborative Group. Frontier Medicine. 2023; 10. doi: 10.3389/fmed.2023.1189140.
  3. Zhang N, Su T, Yan J, Zhang M, Zhao S, Liu C, Chen T. Case report: Successful immunomodulators combined with electromagnetic field therapy in a patient with methazolamide-induced Steven Johnson syndrome/toxic epidermal necrolysis overlap. Frontier Medicine. 2023 May; 10. doi.org/10.3389/fmed.2023.1192920.

2022

  1. Phillips EJ, Bouchard CS, Divito SJ. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis-Coordinating Research Priorities to Move the Field Forward. JAMA Dermatol. 2022 March 30. doi: 10.1001/jamadermatol.2022.0484. Epub ahead of print. PMID: 35353140.
  2. Abtahi, M., Adams, W., Agarwal, A., Agranat, JS., Ajlan, RS., Akhlaq, A. ... Zhu, I.  “Noninfectious Keratitis”, in Ophthalmology, Yanoff M, Duker J, eds., Mosby-Year Book, Inc. St. Louis, MO, 2022.
  3. Bouchard CS. Diagnosis and Management of Blepharitis. Review of Ophthalmology. 2022 September.
  4. Ghosh AK, Bacellar-Galdino M, Iqbal S, Pappenhagen NE, Kaja S. Topical Porphyrin Antioxidant Protects Against Ocular Surface Pathology in a Novel Rabbit Model for Particulate Matter-Induced Dry Eye Disease. J Ocul Pharmacol Ther. 2022 May;38(4):294-304. doi: 10.1089/jop.2021.0131. Epub 2022 Apr 4. PMID: 35384749; PMCID: PMC9125571.
  5. Hakim R, Patel N, Veryovkin I, Gaynes BI. Effect of Age and Viscosity on Duration of Corneal Anesthesia with Topical 2% Lidocaine Administration. J Ocul Pharmacol Ther. 2022 Dec;38(10):709-716. doi: 10.1089/jop.2022.0076. Epub 2022 Nov 14. PMID: 36374966.
  6. Iqbal O, El Khateeb H, Lewis J, Bouchard CS. Immune-mediated pathogenesis of Stevens Johnson Syndrome/Toxic Epidermal Necrolysis - An imminent need for stricter and more effective pharmacovigilance strategies. Journal of Dermatology and Dermatologic Diseases. 2022 December 05-06. 9:33.

2021

  1. Bouchard CS. A Burning Issue. The Ophthalmologist. 2021 June; 20-25.
  2. Metcalfe D, Iqbal O, Chodosh J, Bouchard CS, Saeed H. Acute and Chronic Management of Ocular Disease in Stevens Johnson Syndrome/Toxic Epidermal Necrolysis. Frontiers in Medicine. 2021 July; 8:662897. doi: 10.3389/fmed.2021.662897.
  3. Sadek, Michael; Iqbal, Omer; Siddiqui, Fakiha; Till, Sean; Dharan, Adarsh; Mazariegos, Mellisa; Campbell, Edward; Mudaliar, Kumaran ; Speiser, Jodi ; Bontekoe, Emily; Kouta, Ahmed ; Farooqui, Amber ; Daravath, Bharathi ; Qnebi, Dalia; Sadek, Ramy; Hoppensteadt, Debra; Fareed, Jawed; Bouchard, Charles. The Role of IL-13, IL-15 and granulysin in the pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis. Clinical and Applied Thrombosis/Hemostasis. 2021 February; 27:1076029620950831. doi: 10.1177/1076029620950831. PMID: 33560872.
  4. Iqbal O. A New Eruptive Fever Associated With Stomatitis and Ophthalmia. International Journal of Ophthalmology & Eye Science (IJOES). 2021 July; 9(1e):1-2. 
  5. Goldstein J, Ben Hadj Tahar M, Iqbal O, Fareed J, Bouchard CS. Stevens Johnson Syndrome/Toxic Epidermal Necrolysis and It’s Interface with Coagulation Activation. International Journal of Ophthalmology & Eye Science. 2021; 9(4): 472-477.
  6. de Bustros P, Baldea A, Sanford A, Joyce C, Adams W, Bouchard CS. Review of Culprit Drugs Associated with Patients Admitted to the Burn Unit with the Diagnosis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Syndrome. Journal of the International Society for Burn Injuries. 2021 August; S0305-4179(21)00220-5. doi: 10.1016/j.burns.2021.08.009. PMID: 34924230. PMCID: PMC9124451.
  7. Herrnreiter C, Li XL, Luck M, Zilliox M, Choudhry M. Integrated Analysis of Dysregulated microRNA and mRNA Expression in Intestinal Epithelial Cells following Ethanol Intoxication and Burn Injury. Scientific Reports, 2021 July.
  8. Ghosh AK, Thapa R, Hariani HN, Volyanyuk M, Ogle SD, Orloff KA, Ankireddy S, Lai K, Žiniauskaitė A, Stubbs EB Jr., Kalesnykas G, Hakkarainen JJ, Langert KA, Kaja S. Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress. Pharmaceutics. 2021 August; 13(9):1362. doi.org/10.3390/pharmaceutics13091362. PMID: 34575438. PMCID: PMC8471707.
  9. Zhang CY, Farooq AV, Harocopos GJ, Sollenberger EL, Hou JH, Bouchard CS, Shieh C, Tran UL, Lubniewski AJ, Huang AJ, Paley GL. Corneal perforation in ocular graft-versus-host disease. American Journal of Ophthalmology Case Reports. 2021 December; 24. https://doi.org/10.1016/j.ajoc.2021.101224.

2020

  1. Liu H, Gambino Jr F, Algenio CS, Wu C, Gao YC, Bouchard CS, Qiao L, Bu P, Zhao SZ. Inflammation and Oxidative Stress Induced by Lipid Peroxidation Metabolite 4-Hydroxynonenal in Human Corneal Epithelial Cells. Graefe's Archive for Clinical and Experimental Ophthalmology. 2020 May; 258: 1717-1725. doi: 10.1007/s00417-020-04647-2. PMID: 32445015.
  2. Saeed HN, Bouchard CS, Shieh C, Phillips E, Chodosh J. Highlights from the 2nd Biennial Stevens Johnson Syndrome Symposium 2019: SJS/TEN From Science to Translation. The Ocular Surface. 2020 July; 18(3): 483-486. doi: 10.1016/j.jtos.2019.11.012. PMCID: PMC7307450.
  3. Chang WC, Abe R, Anderson P, Anderson W, Ardern-Jones MR, Meachkofsky TM, Bellon T,  Biala AK, Bouchard CS, Cavalleri GL, Chapman N, Chodosh J, Choi HK, Cibotti RR, Divito SJ, Karen D, Dehaeck U, Etminan M, Forbes D, Fuchs E, Goldman JL, Holmes IV J, Hope EA, Hung SL, Hsieh CL, Lovieno A, Jagdeo J, Kim MK, Koelle DM, Lacouture ME, Le Pallec S, McCawley J, McCawley J, Micheletti RG, Mockenhaupt M, Niemeyer K, Norcross MA, Oboh D, Olteanu C, Pasieka HB, Peter J, Pimohamed M, Rieder M, Saeed HN, Shear NH, Shieh C, Straus S, Sukasem C, Sung C, Trubiano JA, Tsou SY, Ueta M,  Volpi S, Wan C, Wang HS, Wang ZQ, Weintraub J, Whale C, Wheatley LM, Whyte-Croasdaile S, Williams KB, Wright G, Yeung SN, Zhou L, Chung WH, Phillips EJ, Carleton BC. SJS/TEN 2019: From science to translation. Journal of Dermatological Science. 2020 April; 98(1): 2-12. doi: 10.1016/j.jdermsci.2020.02.003. PMCID: PMC7261636.
  4. Ripa M, Jabbehdari S, Yazdanpanah G, Lukacs E, Karcher B, Iqbal O, Bouchard CS.  The Role of Multisystem Disease in Composition of Autologous Serum Tears and ocular surface symptom improvement. The Ocular Surface. 2020 July; 18(3):499-504. doi: 10.1016/j.jtos.2020.02.011. PMID: 32126284.
  5. Sink J, Blatt S, Yoo D, Henry M, Yang DS, Vasaiwala R, Ghadiali L, Adams W, Bouchard CS. A Novel Telemedicine Technique for Evaluation of Ocular Exam Findings via Smartphone Images. Journal of Telemedicine and Telecare. 2020 June. doi: 10.1177/1357633X20926819.  PMID: 32506998. 
  6. Zilliox MJ, Gange WS, Kuffel G, Mores CR, Joyce C, De Bustros P, Bouchard CS. Assessing the Ocular Surface Microbiome in Severe Ocular Surface Diseases. The Ocular Surface. 2020 October; 18(4): 706-712. doi: 10.1016/j.jtos.2020.07.007. PMID: 32717380.

2019

  1. Thompson JM, Truong AH, Stern HD, Djalilian A, Cortina MS, Tu EY, Johnson P, Verdier DD, Rafo L, Lubeck D, Spektor T, Jorgensen C, Rubenstein JB, Majmudar PA, Talati R, Basti S, Feder R, Sugar A, Mian SI, Balasubramanian N, Sandhu J, Gaynes BI, Bouchard CS. A Multicenter Study Evaluating the Risk Factors and Outcomes of Repeat Descemet Stripping Endothelial Keratoplasty. Cornea. 2019 February; 38(2): 177-182. doi: 10.1097/ICO.0000000000001817. PMID: 30615600.
  2. Cortina MS, Karas FI, Bouchard CS, Aref AA, Djalilian A, Vajaranant TS. Staged Ocular Fornix Reconstruction for Glaucoma Drainage Device under Neoconjunctiva at the time of Boston type 1 Keratoprosthesis Implantation. The Ocular Surface. 2019 April; 17(2): 336-340. doi: 10.1016/j.jtos.2019.01.010. PMID: 30742989.
  3. Ziniauskaite A, Ragauskas S, Ghosh AK, Thapa R, Roessler AE, Koulen P, Kalesnykas G, Hakkarainen JJ, Kaja S. Manganese (III) Tetrakis (1-Methyl-4Pyridyl) Porphyrin, a Superoxide Dismutase Mimetic, Reduces Disease Severity in In Vitro and In Vivo Models for Dry-Eye Disease. The Ocular Surface. 2019 April; 17(2): 257-264. doi: 10.1016/j.jtos.2019.02.006. PMCID: PMC6570415.
  4. Gao Y, Li CH, Bu P, Zhang LJ, Bouchard CS. Infectious Interface Keratitis (IIK) Following Lamellar Keratoplasty: A Literature Review. The Ocular Surface. 2019 October; 17(4): 635-643. doi: 10.1016/j.jtos.2019.08.001. PMID: 31415815.

2018

  1. Liu H, Gambino Jr F, Algenio CS, Bouchard CS, Qiao L, Bu P, Zhao SZ. Zidovudine Protects Hyperosmolarity-Stressed Human Corneal Epithelial Cells via Antioxidant Pathway. Biochemical and Biophysical Research Communications. 2018 May; 499(2): 177-181. doi: 10.1016/j.bbrc.2018.03.112. PMID: 29555477.
  2. Till SD, Iqbal O, Dharan A, Campbell E, Bu P, Mudaliar K, Speiser J, Bouchard CS. The Roles of IL-33 and TGF-Β1 in the Pathogenesis of Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis: Potential Biomarkers for Disease Severity. Journal of Ophthalmology Eye Care. 2018 September; 1(1): 105.
  3. White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard CS, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes IV JH, Hung SL, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau, JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ. SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation. Journal of Allergy Clinical Immunology: In Practice. 2018 January; 6(1): 38-69. doi: 10.1016/j.jaip.2017.11.023. PMCID: PMC5857362.
  4. Sward M, Kirk C, Stefonowicz C, Kumar S, Nasir N, Adams W, Bouchard CS. Lax Eyelid Syndrome (LES), Obstructive Sleep Apnea (OSA), and Ocular Surface Inflammation. The Ocular Surface. 2018 July; 16(3): 331-336. doi: 10.1016/j.jtos.2018.04.003. PMID: 29729418.
  5. Gange WS, Kirchner ID, Thompson JA, Hill J, Ibrahim T, Leonetti JP, Anderson DE, Bouchard CS. Ophthalmic complications following acoustic neuroma resection. Operative Neurosurgery. 2018 January; 14(1): 58-65. doi: 10.1093/ons/opx071. PMID: 29253289.

2017

  1. John T, Tighe S, Sheha H, Hamrah P, Salem ZM, Cheng AS, Wang MX, Rock ND. Corneal Nerve Regeneration after Self-Retained Cyropreserved Amniotic Membrane in Dry Eye Disease. 2017 August; 2017: 6404918. doi: 10.1155/2017/6404918. PMCID: PMC5574308.

Cornea Publications (2012-2016)

2016

  1. Hakkarainen JJ, Reinasalo M, Ragauskas S, Seppanen A, Kaja S, Kalesnykas G. Acute cytotoxic effects of marketed ophthalmic formulations on human corneal epithelial cells. International Journal of Pharmaceutics. 2016 September; 511(1):73-78. doi: 10.1016/j.ijpharm.2016.06. PMID: 27374205.
  2. John T, Patel A, Vasavada A, Singh M, Nath V, Cheng AMS, Sheha H. 2016. Effect of Trypan Blue on Descemet's Membrane Elasticity. Cornea. 2016 November; 35(11): 1401-1403. doi: 10.1097/ICO.0000000000000986. PMID: 27538193.
  3. Kohanim S, Palioura S, Saeed HN, Akpek EK, Amescua G, Basu S, Blomquist PH, Bouchard CS, Dart JK, Gai XW, Gomes JAP, Gregory DG, Iyer G, Jacobs DS, Johnson AJ, Kinoshita S, Mantagos IS, Mehta JS, Perez VL, Pflugfelder SC, Sangwan VS, Sippel KC, Sotozono C, Srinivasan B, Tan DTH, Tandon R, Tseng SCG, Ueta M, Chodosh J. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis-A comprehensive review and guide to therapy. I Systemic Disease. The Ocular Surface. 2016 January; 14(1):2-19. doi: 10.1016/j.jtos.2015.10.002. PMID: 26549248.
  4. Kohanim S, Palioura S, Saeed HN, Akpek EK, Amescua G, Basu S, Blomquist PH, Bouchard CS, Dart JK, Gai XW, Gomes JAP, Gregory DG, Iyer G, Jacobs DS, Johnson AJ, Kinoshita S, Mantagos IS, Mehta JS, Perez VL, Pflugfelder SC, Sangwan VS, Sippel KC, Sotozono C, Srinivasan B, Tan DTH, Tandon R, Tseng SCG, Ueta M, Chodosh J. Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease. The Ocular Surface. 2016 April. 14(2): 168-188. doi: 10.1016/j.jtos.2016.02.001. PMID: 26882981.
  5. Sivaraman KR, Jivrajka RV, Soin K, Bouchard CS, Movahedan A, Shorter E, Jain S, Jacobs DS, Djalilian, AR. Superior Limbic Keratoconjunctivitis-like Inflammation in Patients with Chronic Graft-Versus-Host Disease. The Ocular 2016 July; 14(3): 393-400. doi: 10.1016/j.jtos.2016.04.003. PMCID: PMC5554073.

2015

  1. Syed D, Iqbal O, Mosier M, Mitchell R, Hoppensteadt D, Bouchard CS, Fareed J, Gamelli R. Elevated endocan levels and its association with clinical severity in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. International Angiology. 2015; 34(5): 483-8. PMID: 25394955.
  2. Valeshabad AK, Wanek J, Saraf SL, Gaynes BI, Gordeuk VR, Molokie RE, Shahidi M. Changes in Conjunctival Hemodynamics Predict Albuminuria in Sickle Cell Nephropathy. American Journal of Nephrology. 2015 August; 41(6):487-493. doi: 10.1159/000438678. PMCID: PMC4561023.
  3. Valeshabad AK, Wanek J, Gaynes BI, Saraf SL, Molokie R, Shahidi M. Conjunctival microvascular hemodynamics following vaso-occlusive crisis in sickle cell disease. Clinical Hemorheology and Microcirculation. 2015 September; 62(4): 359-367. doi: 10.3233/CH-151977. PMID: 26444608.

2014

  1. Vira S, Abugo U, Shih CY, Udell IJ, Sperling B, Hannush SB, Basti S, Bouchard CS. Descemet stripping endothelial keratoplasty for the treatment of combined Fuchs corneal endothelial dystrophy and Keratoconus. Cornea. 2014 January; 33(1);1-5. doi: 10.1097/ICO.0b013e3182a7389c. PMID: 24240488.

2013

  1. Iqbal O, Fisher G, Vira S, Syed D, Sadeghi N, Freeman D, Campbell E, Sugar J, Feder R, Fareed J, Bouchard CS. Increased expression of secreted frizzled-related protein-1 and microtubule-associated protein light chain 3 in keratoconus. Cornea. 2013 May; 32(5):702-707. doi: 10.1097/ICO.0b013e318282987a. PMID: 23449484.
  2. Vira S, Shih CY, Ragusa N, Sheyman A, Feder R, Weisenthal R, Rosenwasser GOD, Hannush SB, Udell IR, Bouchard CS. Textural interface opacity after Descemet stripping automated endothelial keratoplasty (DSAEK): A report of 30 cases and possible etiology. Cornea. 2013 May; 32(5):54-9. doi: 10.1097/ICO.0b013e31826429d5. PMID: 23132442.

2012

  1. Hsu M, Jayarum A, Verner R, Lin A, Bouchard CS. Indications and Outcomes of Amniotic Membrane Transplantation in the Management of Acute Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Case–Control Study. Cornea. 2012 December; 31(12): 1394-1402. doi: 10.1097/ICO.0b013e31823d02a8. PMID: 23135531.
  2. Chamberlain W, Omid N, Lin A, Farid M, Gaster RN, Steinert RF. Comparison of corneal surface higher-order aberrations after endothelial keratoplasty, femtosecond laser-assistant keratoplasty, and conventional penetrating keratoplasty. Cornea. 2012 January; 31(1): 6-13. doi: 10.1097/ICO.0b013e3182151df2. PMID: 21963860.
  3. Saidel MA, Paik JY, Garcia C, Russo P, Cao DC, Bouchard CS. Prevalence of sleep apnea syndrome and high-risk characteristics among keratoconus patients. Cornea. 2012 June; 31(6): 600–603. doi: 10.1097/ICO.0b013e318243e446. PMID: 22495032.