Profile Image
Franco Laghi Photo
Name
Franco Laghi
Degree
M.D.
FCCP
Rank
Professor
Primary Department
Pulmonary and Critical Care Medicine
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Specialties
Mechanical Ventilation
Breathing Muscle Diseases
COPD
Mechanical Ventilation
Critical Care
Locations
Loyola Hospital
Certifications
Critical Care Medicine, American Board of Internal Medicine Subspecialty
American Board of Internal Medicine Subspecialty Pulmonary Disease
American Board of Internal Medicine
Education
Medical School
Catholic University of the Holy Heart
Residencies
St. Mary's Hospital, Internal Medicine: General
Fellowships
University of Maryland Medical System, Internal Medicine: Critical Care Medicine
Loyola University Medical Center, Pulmonary Medicine
Hobbies
History and Social Studies Books
Publications
Laghi,F.; Khan,N.; Schnell,T.; Aleksonis,D.; Hammond,K.; Shaikh,H.; Collins,E.; Jubran,A.; Tobin,M. J.New device for nonvolitional evaluation of quadriceps force in ventilated patients Muscle & nerve 2018 ;57(5):784-791
Tobin,M. J.; Laghi,F.Extubation, Black Boxes, and Ontology Anesthesiology 2017 ;127(4):599-600
Laghi,F.; Maddipati,V.; Schnell,T.; Langbein,W. E.; Tobin,M. J.Determinants of cough effectiveness in patients with respiratory muscle weakness Respiratory Physiology & Neurobiology 2017 ;240:17-25
Mauri,T.; Yoshida,T.; Bellani,G.; Goligher,E. C.; Carteaux,G.; Rittayamai,N.; Mojoli,F.; Chiumello,D.; Piquilloud,L.; Grasso,S.; Jubran,A.; Laghi,F.; Magder,S.; Pesenti,A.; Loring,S.; Gattinoni,L.; Talmor,D.; Blanch,L.; Amato,M.; Chen,L.; Brochard,L.; Mancebo,J.; PLeUral pressure working Group (PLUG-Acute Respiratory Failure section of the European Society of Intensive Care Medicine)Esophageal and transpulmonary pressure in the clinical setting: meaning, usefulness and perspectives Intensive care medicine 2016 ; :
Kapella,M. C.; Herdegen,J. J.; Laghi,F.; Steffen,A. D.; Carley,D. W.Efficacy and mechanisms of behavioral therapy components for insomnia coexisting with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial TRIALS 2016 ;17(1):258-016-1334-0
Collins,E. G.; Jelinek,C.; O'Connell,S.; Butler,J.; McBurney,C.; Gozali,C.; Reda,D.; Laghi,F.Contrasting breathing retraining and helium-oxygen during pulmonary rehabilitation in COPD: a randomized clinical trial Respiratory medicine 2014 ;108(2):297-306
Shaikh,H.; Laghi,F.Eating on noninvasive ventilation* Critical care medicine 2014 ;42(3):737-738
Laghi,F.; Shaikh,H.Preventing ventilator-induced diaphragmatic dysfunction with phrenic nerve stimulation* Critical care medicine 2014 ;42(2):492-494
Laghi,F.; Shaikh,H. S.; Morales,D.; Sinderby,C.; Jubran,A.; Tobin,M. J.Diaphragmatic neuromechanical coupling and mechanisms of hypercapnia during inspiratory loading Respiratory Physiology & Neurobiology 2014 ;198:32-41
Hammond,K.; You,D.; Collins,E. G.; Leehey,D. J.; Laghi,F.Life-threatening hypokalemia following rapid correction of respiratory acidosis Heart & lung : the journal of critical care 2013 ;42(4):287-289
Laghi,F.; Fernandez,R.Noninvasive ventilation for weaning in hypoxemic respiratory failure: not ready for prime time Intensive care medicine 2012 ;38(10):1583-1585
Laghi,F.; Goyal,A.Auto-PEEP in respiratory failure Minerva anestesiologica 2012 ;78(2):201-221
Lowery,E. M.; Bemiss,B.; Cascino,T.; Durazo-Arvizu,R. A.; Forsythe,S. M.; Alex,C.; Laghi,F.; Love,R. B.; Camacho,P.Low vitamin D levels are associated with increased rejection and infections after lung transplantation. Journal of Heart & Lung Transplantation 2012 ;31(7):700-707
Walter,J. S.; Wurster,R. D.; Zhu,Q.; Laghi,F.Respiratory muscle pacing with chronically implanted intramuscular Permaloc electrodes: A feasibility study. Journal of Rehabilitation Research & Development 2011 ;48(2):103-114
Hussain,O.; Collins,E. G.; Adiguzel,N.; Langbein,W. E.; Tobin,M. J.; Laghi,F.Contrasting pressure-support ventilation and helium-oxygen during exercise in severe COPD. Respiratory medicine 2011 ;105(3):494-505
Laghi,F.Stratification of difficulty in weaning Intensive care medicine 2011 ;37(5):732-734
Walter,J. S.; Wurster,R. D.; Zhu,Q.; Staunton,C.; Laghi,F.Stimulating multiple respiratory muscles with intramuscular Permaloc electrodes The journal of spinal cord medicine 2010 ;33(2):135-143
Tobin,M. J.; Laghi,F.; Jubran,A.Narrative review: ventilator-induced respiratory muscle weakness Annals of Internal Medicine 2010 ;153(4):240-245
Brochard,L.; Abroug,F.; Brenner,M.; Broccard,A. F.; Danner,R. L.; Ferrer,M.; Laghi,F.; Magder,S.; Papazian,L.; Pelosi,P.; Polderman,K. H.An Official ATS/ERS/ESICM/SCCM/SRLF Statement: Prevention and Management of Acute Renal Failure in the ICU Patient: an international consensus conference in intensive care medicine. American Journal of Respiratory & Critical Care Medicine 2010 ;181(10):1128-1155
Laghi,F.Advancing femoral nerve stimulation into the stage of science. Journal of applied physiology 2009 ;106(2):356-357
Laghi,F.; Adiguzel,N.; Tobin,M. J.Endocrinological derangements in COPD European Respiratory Journal 2009 ;34(4):975-996
Tobin,M. J.; Laghi,F.; Brochard,L.Role of the respiratory muscles in acute respiratory failure of COPD: lessons from weaning failure Journal of applied physiology 2009 ;107(3):962-970
Laghi,F.NAVA: brain over machine?. Intensive care medicine 2008 ;34(11):1966-1968
Laghi,F.Weaning: can the computer help?. Intensive care medicine 2008 ;34(10):1746-1748
Collins,E. G.; Langbein,W. E.; Fehr,L.; O'Connell,S.; Jelinek,C.; Hagarty,E.; Edwards,L.; Reda,D.; Tobin,M. J.; Laghi,F.Can ventilation-feedback training augment exercise tolerance in patients with chronic obstructive pulmonary disease?[see comment]. American Journal of Respiratory & Critical Care Medicine 2008 ;177(8):844-852
Kellum,J. A.; Mehta,R. L.; Levin,A.; Molitoris,B. A.; Warnock,D. G.; Shah,S. V.; Joannidis,M.; Ronco,C.; Laghi,F.Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi process. Clinical Journal of The American Society of Nephrology: CJASN 2008 ;3(3):887-894
Himmelfarb,J.; Joannidis,M.; Molitoris,B.; Schietz,M.; Okusa,M. D.; Warnock,D.; Laghi,F.; Goldstein,S. L.; Prielipp,R.; Parikh,C. R.; Pannu,N.; Lobo,S. M.; Shah,S.; D'Intini,V.; Kellum,J. A.Evaluation and initial management of acute kidney injury. Clinical Journal of The American Society of Nephrology: CJASN 2008 ;3(4):962-967
Parthasarathy,S.; Jubran,A.; Laghi,F.; Tobin,M. J.Sternomastoid, rib cage, and expiratory muscle activity during weaning failure. Journal of applied physiology 2007 ;103(1):140-147
Walter,J. S.; Dunn,R. B.; Wurster,R. D.; Laghi,F.Microstimulators and intramuscular hook electrodes for the stimulation of respiratory muscles. Journal of Spinal Cord Medicine 2007 ;30(4):338-345
Laghi,F.; Langbein,W. E.; Antonescu-Turcu,A.; Jubran,A.; Bammert,C.; Tobin,M. J.Respiratory and skeletal muscles in hypogonadal men with chronic obstructive pulmonary disease. American Journal of Respiratory & Critical Care Medicine 2005 ;171(6):598-605
Brack,T.; Jubran,A.; Laghi,F.; Tobin,M. J.Fluctuations in end-expiratory lung volume during Cheyne-Stokes respiration. American Journal of Respiratory & Critical Care Medicine 2005 ;171(12):1408-1413
Jubran,A.; Grant,B. J.; Laghi,F.; Parthasarathy,S.; Tobin,M. J.Weaning prediction: esophageal pressure monitoring complements readiness testing. American Journal of Respiratory & Critical Care Medicine 2005 ;171(11):1252-1259
Topeli,A.; Laghi,F.; Tobin,M. J.Effect of closed unit policy and appointing an intensivist in a developing country Critical care medicine 2005 ;33(2):299-306
Tulaimat,A.; Laghi,F.; Mikrut,K.; Carey,R. B.; Budinger,G. R.Potassium sorbate reduces gastric colonization in patients receiving mechanical ventilation Journal of critical care 2005 ;20(3):281-287
Laghi,F.Assessment of respiratory output in mechanically ventilated patients Respiratory care clinics of North America 2005 ;11(2):173-199
Laghi,F.Low testosterone in chronic obstructive pulmonary disease: does it really matter?. American Journal of Respiratory & Critical Care Medicine 2005 ;172(9):1069-1070
Laghi,F.; Antonescu-Turcu,A.; Collins,E.; Segal,J.; Tobin,D. E.; Jubran,A.; Tobin,M. J.Hypogonadism in men with chronic obstructive pulmonary disease: prevalence and quality of life. American Journal of Respiratory & Critical Care Medicine 2005 ;171(7):728-733
Laghi,F.; Jubran,A.; Topeli,A.; Fahey,P. J.; Garrity,E. R.,Jr; de Pinto,D. J.; Tobin,M. J.Effect of lung volume reduction surgery on diaphragmatic neuromechanical coupling at 2 years. Chest 2004 ;125(6):2188-2195
Road,J.; Jiang,T. X.; Reid,W. D.; Laghi,F.; Tobin,M. J.Weaning failure, muscle injury, and fatigue. American Journal of Respiratory & Critical Care Medicine 2003 ;168(12):1539-40
Collins,E. G.; Fehr,L.; Bammert,C.; O'Connell,S.; Laghi,F.; Hanson,K.; Hagarty,E.; Langbein,W. E.Effect of ventilation-feedback training on endurance and perceived breathlessness during constant work-rate leg-cycle exercise in patients with COPD Journal of Rehabilitation Research & Development 2003 ;40(5):35-44
Laghi,F.; Cattapan,S. E.; Jubran,A.; Parthasarathy,S.; Warshawsky,P.; Choi,Y. S.; Tobin,M. J.Is weaning failure caused by low-frequency fatigue of the diaphragm?[see comment]. American Journal of Respiratory & Critical Care Medicine 2003 ;167(2):120-127
Cattapan,S. E.; Laghi,F.; Tobin,M. J.Can diaphragmatic contractility be assessed by airway twitch pressure in mechanically ventilated patients?. Thorax 2003 ;58(1):58-62
Laghi,F.Effect of inspiratory time and flow settings during assist-control ventilation Current Opinion in Critical care 2003 ;9(1):39-44
Laghi,F.; Tobin,M. J.Disorders of the respiratory muscles American Journal of Respiratory & Critical Care Medicine 2003 ;168(1):10-48
Laghi,F.Curing the septic diaphragm with the ventilator. American Journal of Respiratory & Critical Care Medicine 2002 ;165(2):145-146
Hatipoglu,U.; Laghi,F.; Cattapan,S. E.; Chandrasekhar,A. J.Unilateral expiratory airflow obstruction during forced exhalation. Respiratory care 2002 ;47(6):693-695
Tobin,M. J.; Jubran,A.; Laghi,F.Patient-ventilator interaction American Journal of Respiratory & Critical Care Medicine 2001 ;163(5):1059-1063
Topeli,A.; Laghi,F.; Tobin,M. J.The voluntary drive to breathe is not decreased in hypercapnic patients with severe COPD. European Respiratory Journal 2001 ;18(1):53-60
Laghi,F.; Segal,J.; Choe,W. K.; Tobin,M. J.Effect of imposed inflation time on respiratory frequency and hyperinflation in patients with chronic obstructive pulmonary disease. American Journal of Respiratory & Critical Care Medicine 2001 ;163(6):1365-1370
Laghi,F.Lung volume reduction surgery: friend or foe/ Current Opinion in Critical care 2000 ;6(1):57-65