- Profile Image
- Name
- Nunzia Caporarello
- Degree
- Ph.D.
- Rank
- Assistant Professor
- Primary Department
- Medicine
- Hobbies
- Dancing
- Traveling
- Yoga
- Baking
- Cooking
- Publications
- Giovanni Ligresti, Ahmed A Raslan, Jeongmin Hong, Nunzia Caporarello, Marco Confalonieri, Steven K Huang Mesenchymal cells in the lung: evolving concepts and their role in fibrosis Gene ;
- Ahmend A Raslan, Tho X Pham, Jisu Lee, Jeongmin Hong, Jillian Schmottlach, Kristina Nicholas, Taha Dinc, Andrea M Bujor, Nunzia Caporarello, Aude Thiriot, Ulrich H von Adrian, Steven K Huang, Roberto F Nicosia, Maria Trojanowska, Xaralabos Varelas, Giovanni Ligresti Single cells transcriptomics of fibrotic lungs unveils aging-associated alterations in endothelial and epithelial cell regeneration BIORXIV ;
- Caporarello, N; Ligresti, G Vascular Contribution to Lung Repair and Fibrosis. American journal of respiratory cell and molecular biology ;
- Pham TX, Lee J, Guan J, Jones DL, Caporarello N, Meridew JA, Huang SK, Tschumperlin DJ, Ligresti G Comparative transcriptional analysis of lung fibroblasts from young and aged mice identifies PIM1/NFATc1 axis as a driver of persistent fibrosis JCI insight ;
- Caporarello N, Lee J, Pham TX, Guan J, Jones DL, Link PA, Meridew JA, Marden G, Yamashita T, Huang SK, Nicosia RF, Tschumperlin DJ, Trojanowska M, Ligresti G Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis Nature communications ;
- Qianqian Guo, Kunimaro Furuta, Shahidul Islam, Nunzia Caporarello, Daniel J Tschumperlin, Petra Hirsova, Samar H Ibrahim Liver sinusoidal endothelial cell expressed vascular cell adhesion molecule 1 (VCAM1) promotes liver fibrosis Frontiers in immunology ;
- Ashley Y Gao, Ana M. Diaz Espinosa, Fiorenza Gianì, Tho X. Pham, Chase M. Carver, Aja Aravamudhan, Colleen M. Bartman, Giovanni Ligresti, Nunzia Caporarello, Marissa J. Schafer, Andrew J. Haak Pim-1 Kinase is a positive feedback regulator of the senescent lung fibroblast inflammatory secretome American Journal of Physiology - Lung Cellular & Molecular Physiology ;
- Kalpana R Betageri, Patrick A Link, Andrew J Haak, Giovanni Ligresti, Daniel J Tschumperlin, Nunzia Caporarello The matricellular protein CCN3 promotes lung endothelial homeostasis and function American Journal of Physiology - Lung Cellular & Molecular Physiology ;
- Dakota L Jones, Nunzia Caporarello, Jeffrey A Meridew, Kyoung M Choi, Andrew J Haak, Patrick A Link, Qi Tan, Tamas Ordog, Giovanni Ligresti, Daniel J Tschumperlin Lung injury epigenetically primes mesenchyme for amplified activation upon re-injury BIORXIV ;
- Tan Q, Link PA, Meridew JA, Pham TX, Caporarello N, Ligresti G, Tschumperlin DJ Spontaneous Lung Fibrosis Resolution Reveals Novel Antifibrotic Regulators American Journal of Respiratory Cell & Molecular Biology ;
- Jones DL, Meridew JA, Link PA, Ducharme MT, Lydon KL, Choi KM, Caporarello N, Tan Q, Diaz Espinosa AM, Xiong Y, Lee JH, Ye Z, Yan H, Ordog T, Ligresti G, Varelas X, Tschumperlin DJ ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation Journal of Cell Biology ;
- Nicosia RF, Ligresti G, Caporarello N, Akilesh S, Ribatti D. COVID-19 Vasculopathy: Mounting Evidence for an Indirect Mechanism of Endothelial Injury American Journal of Pathology ;
- Ring N., Volpe MC., Stepisnik T., Mamolo MG., Panov P., Kocev D., Vodret S, Fortuna S., Calabretti A., Rehman M., Colliva A., Camparini L., Marcuzzo T., Bussani R., Scarabellotto S., Confalonieri M., Pham TX., Ligresti G., Caporarello N., Loffredo F., Zampieri D., Dzeroski S., Zacchigna S. Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound inhibiting lung fibrosis through inhibition of myofibroblast differentiation Cell death & disease ;
- Giurdanella G., Longo A., Distefano A., Olivieri M., Cristaldi M., Cosentino A., Agafonova A., Caporarello N., Lupo G., Anfuso CD The Anti-inflammatory Effect of the ß1-Adrenergic Receptor Antagonist Metoprolol on High Glucose Treated Human Microvascular Retinal Endothelial Cells Cells ;
- Aravamudhan A, Haak AJ, Choi KM, Meridew JA, Caporarello N, Jones DL, Tan Q, Ligresti G, Tschumperlin DJ. TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation American journal of physiology.Lung cellular and molecular physiology ;
- Caporarello N, Meridew JA, Aravamudhan A, Jones DL, Austin SA, Pham TX, Haak AJ, Moo Choi K, Tan Q, Haresi A, Huang SK, Katusic ZS, Tschumperlin DJ, Ligresti G Vascular dysfunction in aged mice contributes to persistent lung fibrosis Aging Cell ;
- Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis JCI insight ;
- Caporarello N, Meridew JA, Jones DL, Tan Q, Haak AJ, Choi KM, Manlove LJ, Prakash YS, Tschumperlin DJ, Ligresti G PGC1alpha repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state Thorax ;
- Lupo G, Cambria MT, Olivieri M, Rocco C, Caporarello N, Longo A, Zanghi G, Salmeri M, Foti MC, Anfuso CD Anti-angiogenic effect of quercetin and its 8-methyl pentamethyl ether derivative in human microvascular endothelial cells ;
- Jones DL, Haak AJ, Caporarello N, Choi KM, Ye Z, Yan H, Varelas X, Ordog T, Ligresti G, Tschumperlin DJ. TGFbeta-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression Journal of cell science ;
- Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis Science translational medicine ;
- Caporarello N, D'Angeli F, Cambria MT, Candido S, Giallongo C, Salmeri M, Lombardo C, Longo A, Giurdanella G, Anfuso CD, Lupo G Pericytes in Microvessels: From "Mural" Function to Brain and Retina Regeneration International journal of molecular sciences ;
- Tudisco C, Cambria MT, Giuffrida AE, Sinatra F, Anfuso CD, Lupo G, Caporarello N, Falanga A, Galdiero S, Oliveri V, Satriano C, Condorelli GG Comparison Between Folic Acid and gH625 Peptide-Based Functionalization of Fe3O4 Magnetic Nanoparticles for Enhanced Cell Internalization ;
- Caporarello N, Olivieri M, Cristaldi M, Scalia M, Toscano MA, Genovese C, Addamo A, Salmeri M, Lupo G, Anfuso CD Blood-Brain Barrier in a Haemophilus influenzae Type a In Vitro Infection: Role of Adenosine Receptors A2A and A2B Molecular neurobiology ;
- Caporarello N, Parrino C, Trischitta V, Frittitta L Insulin receptor signaling and glucagon-like peptide 1 effects on pancreatic beta cells PLoS ONE ;
- Di Pietro P, Caporarello N, Anfuso CD, Lupo G, Magri A, La Mendola D, Satriano C . Immobilization of Neurotrophin Peptides on Gold Nanoparticles by Direct and Lipid-Mediated Interaction: A New Multipotential Therapeutic Nanoplatform for CNS Disorders ;
- Caporarello N, Lupo G, Olivieri M, Cristaldi M, Cambria MT, Salmeri M, Anfuso CD Classical VEGF, Notch and Ang signalling in cancer angiogenesis, alternative approaches and future directions ;
- Caporarello N, Olivieri M, Cristaldi M, Rusciano D, Lupo G, Anfuso CD Melanogenesis in uveal melanoma cells: Effect of argan oil International journal of molecular medicine ;
- Giurdanella G, Lazzara F, Caporarello N, Lupo G, Anfuso CD, Eandi CM, Leggio GM, Drago F, Bucolo C, Salomone S Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE Biochemical pharmacology ;
- 33. Lupo G, Caporarello N, Olivieri M, Cristaldi M, Motta C, Bramanti V, Avola R, Salmeri M, Nicoletti F, Anfuso CD Anti-angiogenic Therapy in Cancer: Downsides and New Pivots for Precision Medicine Frontiers in pharmacology ;
- Caporarello N, Salmeri M, Scalia M, Motta C, Parrino C, Frittitta L, Olivieri M, Cristaldi M, Avola R, Bramanti V, Toscano MA, Anfuso CD, Lupo G Cytosolic and Calcium-Independent Phospholipases A2 Activation and Prostaglandins E2 Are Associated with Escherichia coli-Induced Reduction of Insulin Secretion in INS-1E Cells PLoS ONE ;
- Tibullo D, Caporarello N, Giallongo C, Anfuso CD, Genovese C, Arlotta C, Puglisi F, Parrinello NL, Bramanti V, Romano A, Lupo G, Toscano V, Avola R, Brundo MV, Di Raimondo F, Raccuia SA Antiproliferative and Antiangiogenic Effects of Punica granatum Juice (PGJ) in Multiple Myeloma (MM) Nutrients ;
- Olivieri M, Amata E, Vinciguerra S, Fiorito J, Giurdanella G, Drago F, Caporarello N, Prezzavento O, Arena E, Salerno L, Rescifina A, Lupo G, Anfuso CD, Marrazzo A Antiangiogenic Effect of (+/-)-Haloperidol Metabolite II Valproate Ester [(+/-)-MRJF22] in Human Microvascular Retinal Endothelial Cells ;
- Giurdanella G, Anfuso CD, Olivieri M, Lupo G, Caporarello N, Eandi CM, Drago F, Bucolo C, Salomone S Aflibercept, bevacizumab and ranibizumab prevent glucose-induced damage in human retinal pericytes in vitro, through a PLA2/COX-2/VEGF-A pathway Biochemical pharmacology ;
- Anfuso CD, Olivieri M, Bellanca S, Salmeri M, Motta C, Scalia M, Satriano C, La Vignera S, Burrello N, Caporarello N, Lupo G, Calogero AE Asthenozoospermia and membrane remodeling enzymes: a new role for phospholipase A2 Andrology : open access ;
- Caporarello N, Salmeri M, Scalia M, Motta C, Parrino C, Frittitta L, Olivieri M, Toscano MA, Anfuso CD, Lupo G Role of cytosolic and calcium independent phospholipases A(2) in insulin secretion impairment of INS-1E cells infected by S. aureus FEBS letters ;
- 37. Patane G*, Caporarello N*, Marchetti P, Parrino C, Sudano D, Marselli L, Vigneri R, Frittitta L. Adiponectin increases glucose-induced insulin secretion through the activation of lipid oxidation Acta diabetologica ;
- Di Paola R, Caporarello N, Marucci A, Dimatteo C, Iadicicco C, Del Guerra S, Prudente S, Sudano D, Miele C, Parrino C, Piro S, Beguinot F, Marchetti P, Trischitta V, Frittitta L. ENPP1 affects insulin action and secretion: evidence from in vitro studies PLoS ONE ;